Phenotype Image Detail

Image

Caption

Mcph1^tm1.2Kali/Mcph1^tm1.2Kali (BRIT1-/-) ovaries were smaller than wild-type (WT) and had no ovarian follicles. (A) Mutant ovaries were much smaller than WT. The relative weight of ovaries from WT and mutant mice at P35 were calculated. (B) There was no ovarian follicles in mutant ovaries. The WT and mutant ovary tissues were sectioned and stained with H&E. Shown here are the ovaries at postnatal days 8. Black arrows, the whole ovaries; blue arrows, primary follicles. Scale bar, 0.2 mm.

Copyright

This image is from Liang Y, PLoS Genet 2010 Jan;6(1):e1000826, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:156371

Associated Alleles

Symbol	Name
Mcph1^tm1.2Kali	microcephaly, primary autosomal recessive 1; targeted mutation 1.2, Kaiyi Li

Associated Genotypes

Allelic Composition	Genetic Background
Mcph1^tm1.2Kali/Mcph1^tm1.2Kali	involves: 129S7/SvEvBrd * C57BL/6J