Phenotype Image Detail

Image

Caption

H&E staining of skin sections from two-week-old Rassf9^{Tg(PDLIM7*)2Cml}/Rassf9^{Tg(PDLIM7*)2Cml} (-/-) mice show abnormalities. The dashed yellow lines denote the epidermis-dermis and dermis-adipose borders. Similar results were obtained from three independent pairs of mice. The low and high magnification images were shown in the left and right panels, respectively. Hematoxylin and eosin (H&E) staining of fixed skin tissue sections revealed thickening of the epidermis and dermis and thinning of the subcutaneous adipose tissue in mutants. Left panel, scale bar = 200 um; Right panel, scale bar = 20 um. Epi, epidermis; Der, dermis; Adi, adipose; HF, hair follicle.

Copyright

This image is from Lee CM, PLoS One 2011;6(3):e17867, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:171677

Associated Alleles

Symbol	Name
Rassf9^Tg(PDLIM7*)2Cml	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; transgene insertion 2, Chiou-Mei Lee

Associated Genotypes

Allelic Composition	Genetic Background
Rassf9^Tg(PDLIM7*)2Cml/Rassf9^Tg(PDLIM7*)2Cml	involves: ICR