Phenotype Image Detail

Image

Caption

Lateral views of the craniofacial skeletons of E18.5 Ednra^tm1Hku/Ednra⁺ (Ednra^Neo/+) ES cell-derived and Ednra^{tm7(Hand2)Hku}/Ednra⁺ (Ednra^Hand2/+) ES cell-derived chimeric mice with schematic representations. The maxillary and mandibular elements are in yellow and red, respectively. Transformed parts of the maxillary structures are colored with orange. dnt, dentary; etm, ectotympanic; fmx, frontal process of maxilla; gn, gonial; hy, hyoid; in, incus; jg, jugal; la, lacrimal; ma, malleus; mx, maxilla; pmx, premaxilla; sp, styloid process; sq, squamosal; st, stapes; *, ectopic structure.

Copyright

This image is from Sato T, Proc Natl Acad Sci U S A 2008 Dec 2;105(48):18806-11. Copyright 2008 National Academy of Sciences, U.S.A. J:224515

Associated Alleles

Symbol	Name
Ednra^tm7(Hand2)Hku	endothelin receptor type A; targeted mutation 7, Hiroki Kurihara

Associated Genotypes

Allelic Composition	Genetic Background
Ednra^tm7(Hand2)Hku/Ednra^+	chimera involves: 129 * C57BL/6 * ICR