Phenotype Image Detail

Image

Caption

Decreased susceptibility to CVB3 viral infection of the heart in Dmd^tm1.1Know/Dmd^tm1.1Know mice. Sarcolemma permeability (EBD uptake) and myocyte damage (von Kossa staining) are significantly reduced in the hearts of the mutant mice 8 days post-infection. Scale bars: 500 um (200 um, enlargements). Quantified results represent the mean SEM. *P < 0.05; ***P < 0.001; each data point is represented on graphs.

Copyright

This image is from Lim BK, J Clin Invest 2013 Dec 2;123(12):5146-51 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:207775

Associated Alleles

Symbol	Name
Dmd^tm1.1Know	dystrophin, muscular dystrophy; targeted mutation 1.1, Kirk Knowlton

Associated Genotypes

Allelic Composition	Genetic Background
Dmd^tm1.1Know/Dmd^tm1.1Know	involves: C3H