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Phenotype Image Detail
Image
Caption Sternum and kidneys are abnormal in Fras1bfb/Fras1bfb embryos. Sternabrae are misaligned in mutant mice at E18.5 (B), when compared to the sternum of wild-type (Fras1+/+) embryos of the same age (A). Analysis of the internal organs of wild-type (C and E) and mutant (D and F) mice show no identifiable kidneys in the majority of the mutants (asterisk in D). A blood-filled blister is also present in the hindlimb of this embryo (arrowhead in D). Transverse sections of an E17.5 mutant show a large void where the kidney should be located (asterisk in F). A, adrenal gland; K, kidneys.
Copyright This image is from Miller KA, PLoS One 2013;8(10):e76342, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:208682
Associated
Alleles
Symbol Name
Fras1bfb Fraser extracellular matrix complex subunit 1; blood filled blisters
Associated
Genotypes
Allelic Composition Genetic Background
Fras1bfb/Fras1bfb involves: C57BL/6JAnu

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory