Phenotype Image Detail

Image

Caption

Sternum and kidneys are abnormal in Fras1^bfb/Fras1^bfb embryos. Sternabrae are misaligned in mutant mice at E18.5 (B), when compared to the sternum of wild-type (Fras1^+/+) embryos of the same age (A). Analysis of the internal organs of wild-type (C and E) and mutant (D and F) mice show no identifiable kidneys in the majority of the mutants (asterisk in D). A blood-filled blister is also present in the hindlimb of this embryo (arrowhead in D). Transverse sections of an E17.5 mutant show a large void where the kidney should be located (asterisk in F). A, adrenal gland; K, kidneys.

Copyright

This image is from Miller KA, PLoS One 2013;8(10):e76342, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:208682

Associated Alleles

Symbol	Name
Fras1^bfb	Fraser extracellular matrix complex subunit 1; blood filled blisters

Associated Genotypes

Allelic Composition	Genetic Background
Fras1^bfb/Fras1^bfb	involves: C57BL/6JAnu