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Phenotype Image Detail
Image
Caption Representative sections of the middle ear and Eustachian tube mucosae of wild-type (WT) and Chd7Ome/Chd7+ littermates. Few goblet cells could be found in the middle ear (A) and Eustachian tube mucosae (C) of wild-type littermate mice. By contrast, goblet cells were present at high density among other cells in the epithelium of the middle ear cavity (B) and the duct of the Eustachian tube (D) of mutant mice (typical goblet cells are indicated by arrows). Goblet cells have a distinctly polarized morphology in which the nucleus stains black in color at the cell base, and the mucus stains a deep rose color in the middle and apical portions of the cell. Scale bars = 50 um.
Copyright This image is from Tian C, PLoS One 2012;7(4):e34944, an open-access article distributed under the terms of the Creative Commons Attribution License. J:187200
Associated
Alleles
Symbol Name
Chd7Ome chromodomain helicase DNA binding protein 7; Otitis media and eye defects
Associated
Genotypes
Allelic Composition Genetic Background
Chd7Ome/Chd7+ involves: BALB/cByJ * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/31/2018
MGI 6.12
The Jackson Laboratory