Phenotype Image Detail

Image

Caption

Phenotype of chimeric Porcn genetrap mouse, Porcn^{Gt(CSD256)Byg}/Y. (B) Fused and hypoplastic shortened digits. (C) Areas of hypoplastic skin with alopecia (black arrows) and swelling at lower back. (E) Skeletal microCT images showing fusion and hypoplasia of digits in mutant mouse (WT, wild-type mouse; CSD, mouse generated from CSD256, Porcn^{Gt(CSD256)Byg}/Y; inset, enlargement of hindpaw). (F) Hypoplastic skin with dermoid cyst (*). Scale bar represents 1 mm. (G) Top panel: ovary and oviducts (scale bar represents 200 mm). Bottom panel: hypoplastic testis (scale bar represents 100 um). (H) Top panel: hydronephrotic kidney with thin medulla. Bottom panel: contralateral normal kidney (scale bars represent 1 mm).

Copyright

This image is from Liu W, PLoS One 2012;7(3):e32331, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:186934

Associated Alleles

Symbol	Name
Porcn^Gt(CSD256)Byg	porcupine O-acyltransferase; gene trap CSD256, BayGenomics

Associated Genotypes

Allelic Composition	Genetic Background
Porcn^Gt(CSD256)Byg/Y	chimera involves: 129P2/OlaHsd