Phenotype Image Detail

Image

Caption

Coronal sections through the heart of wild-type (L,N) and Gata4^tm1Grg/Gata4⁺ (Gata4 G295S^ki/wt) (M,O) E12.5 hearts. High magnification images of the atria (L,M) and ventricle (N,O) are shown. Quantitative analysis demonstrates decreased wall thickness in the (P) atria and (Q) compact ventricular myocardium in heterozygous mutants as compared to wild-type littermates (n = 3 for each genotype). Arrowheads, representative site of measurement; *, p value <0.05. Scale bars indicate 200 um.

Copyright

This image is from Misra C, PLoS Genet 2012 May;8(5):e1002690, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:185124

Associated Alleles

Symbol	Name
Gata4^tm1Grg	GATA binding protein 4; targeted mutation 1, Vidu Garg

Associated Genotypes

Allelic Composition	Genetic Background
Gata4^tm1Grg/Gata4^+	involves: 129 * C57BL/6