Phenotype Image Detail

Image

Caption

Whole-mount IHC for neurofilaments in retinas of P4 Sema3e^tm1Ddg/Sema3e^tm1Ddg (Sema3e^-/-) mice. Note the transverse axonal bundling and/or branching in small areas of the Sema3e^tm1Ddg/Sema3e^tm1Ddg retina compared with the parallel axon alignment in the Sema3e^tm1Ddg/Sema3e⁺ (Sema3e^+/-) retina. Scale bar: 20 um.

Copyright

This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943

Associated Alleles

Symbol	Name
Sema3e^tm1Ddg	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; targeted mutation 1, David D Ginty

Associated Genotypes

Allelic Composition	Genetic Background
Sema3e^tm1Ddg/Sema3e^tm1Ddg	involves: 129P2/OlaHsd * C57BL/6