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Phenotype Image Detail
Image
Caption (A-H) Whole-mount IHC for PECAM-1 in P4 retinas. Sema3etm1Ddg/Sema3etm1Ddg (Sema3e-/-) retinas display a variety of vascular defects, including solitary clusters of retinal endothelial cells (ECs) isolated from the advancing vascular fronts (B and C), attachment of hyaloid vessels to the retinal surfaces (C-H), intraretinal vascular tufts (F), and poor development of morphologically distinct arteries and veins (D-H). Scale bar: 100 um.
Copyright This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943
Associated
Alleles
Symbol Name
Sema3etm1Ddg sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; targeted mutation 1, David D Ginty
Associated
Genotypes
Allelic Composition Genetic Background
Sema3etm1Ddg/Sema3etm1Ddg involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory