About   Help   FAQ
Phenotype Image Detail
Image
Caption (D) Quantification of filopodium length (n = 18 per group) and filopodium number/100 um vessel length (n = 7 per group) at the sprouting vascular fronts, and vascular density (n = 4 per group) in P4 controls and Sema3etm1Ddg/Sema3etm1Ddg (Sema3e-/-) retinas. Error bars represent SEM; ***p < 0.001, *p < 0.05. (E) Triple labeling for neurofilaments (green), PECAM-1 (red), and nuclei (blue) in retinal sections of P4 mutant mice. The superficial vessels (arrowheads) over the neuronal axons ectopically invade the ganglion cell layer (GCL) of the homozygous mutant mice (arrow). Scale bars: 20 um (E).
Copyright This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943
Associated
Alleles
Symbol Name
Sema3etm1Ddg sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; targeted mutation 1, David D Ginty
Associated
Genotypes
Allelic Composition Genetic Background
Sema3etm1Ddg/Sema3etm1Ddg involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/11/2014
MGI 5.20
The Jackson Laboratory