Phenotype Image Detail

Image

Caption

A Irf6^clft1/Irf6^clft1 (clft1) mutant at P0.5 (b) with apparently shortened forelimbs as compared to E18.5 wild-type (wt, a). (c) An E18.5 fetus with syndactyly. (d-f) Skeletal preparations to highlight bone and cartilage. Note the fusion of phalanges on an otherwise normal Irf6^clft1/Irf6^clft1 limb (e,f).

Copyright

This image is from Stottmann RW, Genesis 2010 May;48(5):303-8, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:160190

Associated Alleles

Symbol	Name
Irf6^clft1	interferon regulatory factor 6; cleft palate 1

Associated Genotypes

Allelic Composition	Genetic Background
Irf6^clft1/Irf6^clft1	involves: A/J * FVB