Phenotype Image Detail

Image

Caption

Testicular morphology of wild-type versus Hsf2^tm1Miv/Hsf2^tm1Miv and Hsf1^tm1Miv/Hsf1^tm1Miv Hsf2^tm1Miv/Hsf2^tm1Miv mice. Testes recovered from adult (12-week old) wild-type (+/+), Hsf2^tm1Miv/Hsf2^tm1Miv (hsf2-/-), or Hsf1^tm1Miv/Hsf1^tm1Miv Hsf2^tm1Miv/Hsf2^tm1Miv (hsf1-/-/hsf2-/-) mice were inspected macroscopically. Note the dramatic reduction in testicular size in the double homozygous mice compared to wild-type. x10.

This image is from Wang G, Genesis 2004 Feb;38(2):66-80, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:88035

Associated
Alleles

Symbol	Name
Hsf1^tm1Miv	heat shock factor 1; targeted mutation 1, Nahid F Mivechi
Hsf2^tm1Miv	heat shock factor 2; targeted mutation 1, Nahid F Mivechi

Associated
Genotypes

Allelic Composition	Genetic Background
Hsf2^tm1Miv/Hsf2^tm1Miv	involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Hsf1^tm1Miv/Hsf1^tm1Miv Hsf2^tm1Miv/Hsf2^tm1Miv	involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

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