Phenotype Image Detail

Image

Caption

Electron microscopy analysis of lungs from wild-type and Abca3^tm1Nina/Abca3^tm1Nina mice at birth. A, numerous properly formed lamellar bodies (asterisks), apical microvilli (MV), and alveolar surfactant were observed in the wild-type lung. B and C, by contrast, smaller, lamellar body-like organelles with dense peripheral inclusions (arrows) were observed in the Abca3^tm1Nina/Abca3^tm1Nina lung. Scale bars: 2 um in A and B; 500 nm in C.

Copyright

This image is from Ban N, J Biol Chem 2007 Mar 30;282(13):9628-34 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:121155

Associated Alleles

Symbol	Name
Abca3^tm1Nina	ATP-binding cassette, sub-family A member 3; targeted mutation 1, Nobuya Inagaki

Associated Genotypes

Allelic Composition	Genetic Background
Abca3^tm1Nina/Abca3^tm1Nina	involves: 129P2/OlaHsd * C57BL/6J