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Phenotype Image Detail
Image
Caption A: Male and female Irak3tm1Flv/Irak3tm1Flv (IRAK-M-/-) mice are smaller than wild-type (IRAK-M+/+) mice; n=10. B: microCT analysis of distal femurs from 4 month old mutant and wild-type male mice. Note the paucity of the trabeculae inside the bone in mutant mice. The wider diameter of the bone sections measures ~3 mm. Bar, 1 mm. C: Toluidine blue staining of sections from epiphyseal bones from 4 month old mutant and wild-type male mice. Bar, 1 mm. D: TRAP staining of sections from epiphyseal bones from 4 month old mutant and wild-type male mice. Bar, 200 um.
Copyright This image is from Li H, J Exp Med 2005 Apr 4;201(7):1169-77, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:98035
Associated
Alleles
Symbol Name
Irak3tm1Flv interleukin-1 receptor-associated kinase 3; targeted mutation 1, Richard A Flavell
Associated
Genotypes
Allelic Composition Genetic Background
Irak3tm1Flv/Irak3tm1Flv involves: 129S1/Sv * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory