About   Help   FAQ
Phenotype Image Detail
Image
Caption Electron microscopy of the distal tubular epithelial cells of Hsd11b2tm1Yko/Hsd11b2tm1Yko (A) and wild-type mice (B). Distal tubular epithelial cells from mutant mice show an increase in size. The subnuclear, or basal, pole is expanded with apical displacement of the nucleus. The number of mitochondria (m) in each distal tubular cell is increased, although the mitochondria remain located at the expanded basal pole (bm, basal membrane). Occasional membrane-enclosed vacuoles (v) are seen in the cytoplasm of the distal tubular epithelial cells from the mutant mice. x3,800.
Copyright This image is from Kotelevtsev Y, J Clin Invest 1999 Mar;103(5):683-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:53391
Associated
Alleles
Symbol Name
Hsd11b2tm1Yko hydroxysteroid 11-beta dehydrogenase 2; targeted mutation 1, Yuri V Kotelevtsev
Associated
Genotypes
Allelic Composition Genetic Background
Hsd11b2tm1Yko/Hsd11b2tm1Yko involves: 129P2/OlaHsd * MF1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory