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Phenotype Image Detail
Image
Caption Toluidine blue-stained sections of the saccule of 5-6 week old wild-type (+/+, A) and Atp2b2tm1Ges/Atp2b2tm1Ges (-/-, B) mice. The macula (M), a neuroepithelial plaque containing the sensory hair cells and lying immediately beneath the gelatinous otolithic membrane (OM), appears histologically similar in mice of both genotypes. Innervation (open arrowheads) of the macula is also histologically similar in both genotypes. Otoconia (arrow), the calcium carbonate crystals embedded in the otolithic membrane, are absent in mutant mice. Scale bar, 50 um.
Copyright This image is from Kozel PJ, J Biol Chem 1998 Jul 24;273(30):18693-6 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:48863
Associated
Alleles
Symbol Name
Atp2b2tm1Ges ATPase, Ca++ transporting, plasma membrane 2; targeted mutation 1, Gary E Shull
Associated
Genotypes
Allelic Composition Genetic Background
Atp2b2tm1Ges/Atp2b2tm1Ges involves: 129/Sv * 129X1/SvJ * Black Swiss

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory