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Phenotype Image Detail
Image
Caption A: Cataract incidence of wild type, Bub3tm1Jvd/Bub3+, Rae1tm1Jvd/Rae1+ and Bub3tm1Jvd/Bub3+ Rae1tm1Jvd/Rae1+ mice as detected by the use of slit light after dilating the eyes. The asterisk indicates that the curve is statistically different from that of wild type mice using a log-rank test. B: Overt cataract detected in a 15 month old double heterozygous mouse. C: Cross section of a cataractous lens from a 15 month old double heterozygous mouse stained with hematoxylin and eosin. Note that the posterior portion of the eye has Morgagnian globules, whereas the inner portion has profound calcification. Bar, 1mm.
Copyright This image is from Baker DJ, J Cell Biol 2006 Feb 13;172(4):529-40, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:105717
Associated
Alleles
Symbol Name
Bub3tm1Jvd budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae); targeted mutation 1, Jan M A van Deursen
Rae1tm1Jvd RAE1 RNA export 1 homolog (S. pombe); targeted mutation 1, Jan M A van Deursen
Associated
Genotypes
Allelic Composition Genetic Background
Bub3tm1Jvd/Bub3+
Rae1tm1Jvd/Rae1+
Not Specified

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory