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Phenotype Image Detail
Image
Caption A-D: Representative photographs of wild type and Bub3tm1Jvd/Bub3+ Rae1tm1Jvd/Rae1+ mice at 5 (A and B) and 27 months (C and D). Note the overt cataract, severe lordokyphosis, and cachetic appearance of the 27 month old double heterozygous mouse pictured in D. E: Overall survival curves for wild type, Bub3tm1Jvd/Bub3+, Rae1tm1Jvd/Rae1+ and double heterozygous mice. The curve marked with an asterisk is significantly different from that of wild type mice using a log-rank test.
Copyright This image is from Baker DJ, J Cell Biol 2006 Feb 13;172(4):529-40, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:105717
Associated
Alleles
Symbol Name
Bub3tm1Jvd BUB3 mitotic checkpoint protein; targeted mutation 1, Jan M A van Deursen
Rae1tm1Jvd ribonucleic acid export 1; targeted mutation 1, Jan M A van Deursen
Associated
Genotypes
Allelic Composition Genetic Background
Bub3tm1Jvd/Bub3+
Rae1tm1Jvd/Rae1+
Not Specified

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory