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Phenotype Image Detail
Image
Caption A: Spred2Gt(XB228)Byg/Spred2Gt(XB228)Byg (ko, lower) and wild type (wt, upper) littermates at P1 (left panel) and 8 weeks of age (right panel), demonstrating achondroplasia-like dwarf phenotype shortly after birth and in adulthood. B: X-rays of mutant and wild type littermates at 8 weeks of age, showing generally reduced skeletal growth.
Copyright This image is from Bundschu K, J Biol Chem 2005 Aug 5;280(31):28572-80 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:100826
Associated
Alleles
Symbol Name
Spred2Gt(XB228)Byg sprouty-related EVH1 domain containing 2; gene trap XB228, BayGenomics
Associated
Genotypes
Allelic Composition Genetic Background
Spred2Gt(XB228)Byg/Spred2Gt(XB228)Byg involves: 129P2/OlaHsd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory