About   Help   FAQ
Phenotype Image Detail
Image
Caption Hindlimbs of newborn wild type mouse (C) and newborn Bmp2tm1Cjt/Bmp2tm1Cjt Bmp4tm1Jfm/Bmp4tm1Jfm Tg(Prrx1-cre)1Cjt/0 mouse (D). E & F: Wild type and mutant respectively, showing acridine orange stained hindlimbs of E15.5 mouse embryos. Acridine orange stain is yellow. G & H: Enlarged views of selected regions from (E) and (F), respectively. Black arrows in (G) and (H) show acridine orange stained apoptotic cells in the interdigital mesenchyme, and asterisk in (H) shows the remnant of the apical ectodermal ridge (AER). I & J: Fgf8 mRNA expression in the hindlimbs of #13.5 wild type (I) and mutant (J) embryos. THe thick black arrows in (J) show Fgf8 mRNA expression.
Copyright This image is from Bandyopadhyay A, PLoS Genet 2006 Dec 22;2(12):e216, an open-access article distributed under the terms of the Creative Commons Attribution License. J:118257
Associated
Alleles
Symbol Name
Bmp2tm1Cjt bone morphogenetic protein 2; targeted mutation 1, Clifford J Tabin
Bmp4tm1Jfm bone morphogenetic protein 4; targeted mutation 1, James F Martin
Tg(Prrx1-cre)1Cjt transgene insertion 1, Clifford J Tabin
Associated
Genotypes
Allelic Composition Genetic Background
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory