Phenotype Image Detail

Image

Caption

A: Hematoxylin and eosin staining of quadricep cross sections from Mtm1^tm1.1Jman/Y (upper) and wild type (lower) mice at postnatal day 15. B: Mutant mice are affected by a generalized centronuclear myopathy. Hematoxylin/eosin staining of mutant (upper) and wild type (lower) muscle cross sections from 6 week old mice. (Left, biceps cruralis; Right, triceps crachii). Vacuoles of various sizes in the sarcoplasm of fibers are often present. Magnifications: A; x1000; B: x630

Copyright

This image is from Buj-Bello A, Proc Natl Acad Sci U S A 2002 Nov 12;99(23):15060-5. Copyright 2002 National Academy of Sciences, U.S.A. J:81791

Associated Alleles

Symbol	Name
Mtm1^tm1.1Jman	X-linked myotubular myopathy gene 1; targeted mutation 1.1, Jean-Louis Mandel

Associated Genotypes

Allelic Composition	Genetic Background
Mtm1^tm1.1Jman/Y	involves: 129T1/Sv * C57BL/6