Phenotype Image Detail

Image

Caption

Whole mounts of Pkd1^tm1Maa/Pkd1^tm1Maa (B,D,F,H,J, & K) and age matched wild type embryos (A,C,E,G, & I). Localized hemorrhages and s.c. edema (arrows) distributed over the body surface, with punctate and localized hemorrhages seen in the head (B, D & J) and toes (H & K) of homozygous mutant (J, H & K) but not wild type (A,C,E, G & I) unstained embryos. At E15.5, fatal hemorrhages and edema are seen in the mutant embryos. (H).

Copyright

This image is from Kim K, Proc Natl Acad Sci U S A 2000 Feb 15;97(4):1731-6. Copyright 2000 National Academy of Sciences, U.S.A. J:68331

Associated Alleles

Symbol	Name
Pkd1^tm1Maa	polycystin 1, transient receptor potential channel interacting; targeted mutation 1, M Armin Arnout

Associated Genotypes

Allelic Composition	Genetic Background
Pkd1^tm1Maa/Pkd1^tm1Maa	involves: 129S4/SvJae * C57BL/6