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Phenotype Image Detail
Image
Caption Panels A and B. Four week old littermates, +/+ wildtype (left) and Fgfr2tm4Lni/+ (right). The Fgfr2tm4Lni/+ skulls are rounded due to shortening of the rostrocaudal axis. Arrows indicate obliterated coronal and fusion of the lambdoid sutures. Arrowheads point to normal basioccipital-exoccipital-basisphenoid synchondroses in the wildtype (left) in contrast to the loss of function mutation in the precociously fused Fgfr2tm4Lni/+ mouse (right). Panel C. Histological coronal suture sections frontal and parietal bones at E16.5 and obliterated suture at P29 (arrows). Abbreviations: frontal (f); parietal (p). Scalebars, 200um.
Copyright This image is from Eswarakumar VP, Proc Natl Acad Sci U S A 2004 Aug 24;101(34):12555-60. Copyright 2004 National Academy of Sciences, U.S.A. J:92433
Associated
Alleles
Symbol Name
Fgfr2tm4Lni fibroblast growth factor receptor 2; targeted mutation 4, Peter Lonai
Associated
Genotypes
Allelic Composition Genetic Background
Fgfr2tm4Lni/Fgfr2+ Not Specified

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory