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Phenotype Image Detail
Image
Caption Panel A. Normal appearing kidney of Bcl2tm+/Bcl2+ and Bcl2tm1Dlo/Bcl2+ mice (left and center, respectively) contrast with kidney from Bcl2tm1Dlo/Bcl2tm1Dlo mouse (right), which is small, pale and rough. Panel C and C show histological sections from kidneys of Bcl2tm+/Bcl2+ (B) and Bcl2tm1Dlo/Bcl2tm1Dlo (C) mice. Bcl2tm1Dlo/ Bcl2tm1Dlo kidneys have fewer glomeruli and proximal renal tubules are dilated, with hypertrophic epithelium.
Copyright This image is from Nakayama K, Proc Natl Acad Sci U S A 1994 Apr 26;91(9):3700-4. Copyright 1994 National Academy of Sciences, U.S.A. J:73660
Associated
Alleles
Symbol Name
Bcl2tm1Dlo B cell leukemia/lymphoma 2; targeted mutation 1, Dennis Y Loh
Associated
Genotypes
Allelic Composition Genetic Background
Bcl2tm1Dlo/Bcl2tm1Dlo involves: 129P2/OlaHsd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory