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Phenotype Image Detail
Caption Tyrp1B-lt/Tyrp1B-lt are distinguished from normal by 2 weeks of age. The hair tips are brown, the rest of the hair shaft is white, often creating a mosaic coat color pattern. Base of hairs become lighter as more pigment is lost with age, older mice are a pale gray in color. Pigment loss is due to premature melanocyte death mediated by natural toxicity of pigment production.
Copyright Photo donated for Mouse Genome Informatics database use. J:110244
Symbol Name
Tyrp1B-lt tyrosinase-related protein 1; light
Allelic Composition Genetic Background
Tyrp1B-lt/Tyrp1B-lt LT/SvEiJ

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory