PDE4B Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	PDE4B	HGNC:8781 (HGNC) 5142 (Entrez Gene) 600127 (OMIM) PDE4B (Alliance of Genome Resources)	Chr1 p31.3	Chr1:65792510-66374579 (+) GRCh38	alcohol dependence	Q07343 (UniProt \| EBI) NM_001037339 (RefSeq)
mouse	Pde4b	MGI:99557 (MGI) 18578 (Entrez Gene) Gene Tree Pde4b (Alliance of Genome Resources)	Chr4 46.99 cM	Chr4:101944740-102464456 (+) GRCm39		ENSMUSG00000028525 (Ensembl Gene Model) ENSMUSP00000102524 (Ensembl) ENSMUST00000106911 (Ensembl)
rat	Pde4b	RGD:3280 (Rat Genome Database) 24626 (Entrez Gene) Pde4b (Alliance of Genome Resources)	Chr5 q33			P14646 (UniProt \| EBI) NM_017031 (RefSeq)
zebrafish	pde4ba	ZDB-GENE-030131-9570 (Zebrafish Model Organism Database) 565706 (Entrez Gene) pde4ba (Alliance of Genome Resources)	Chr6			XP_021332832 (RefSeq)
zebrafish	pde4bb	ZDB-GENE-070912-454 (Zebrafish Model Organism Database) 555599 (Entrez Gene) pde4bb (Alliance of Genome Resources)	Chr2			XP_021324251 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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