PROC Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	PROC	HGNC:9451 (HGNC) 5624 (Entrez Gene) 612283 (OMIM) PROC (Alliance of Genome Resources)	Chr2 q14.3	Chr2:127418427-127429242 (+) GRCh38	acute kidney failure antiphospholipid syndrome asthma autosomal dominant thrombophilia due to protein C deficiency autosomal recessive thrombophilia due to protein C deficiency central retinal vein occlusion placental abruption pre-eclampsia protein C deficiency thrombophilia thrombophilia due to activated protein C resistance thrombosis toxic shock syndrome	P04070 (UniProt \| EBI) NM_001375604 (RefSeq)
mouse	Proc	MGI:97771 (MGI) 19123 (Entrez Gene) Gene Tree Proc (Alliance of Genome Resources)	Chr18 17.94 cM	Chr18:32256179-32272623 (-) GRCm39		19123 (NCBI Gene Model) P33587 (UniProt \| EBI) NM_001042768 (RefSeq)
rat	Proc	RGD:3411 (Rat Genome Database) 25268 (Entrez Gene) Proc (Alliance of Genome Resources)	Chr18 p12			P31394 (UniProt \| EBI) NM_012803 (RefSeq)
zebrafish	proca	ZDB-GENE-060824-5 (Zebrafish Model Organism Database) 393327 (Entrez Gene) proca (Alliance of Genome Resources)	Chr2			NP_956650 (RefSeq) NM_200356 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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