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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human OTC HGNC:8512 (HGNC)
5009 (Entrez Gene)
300461 (OMIM)
HGNC homology
ChrX p21.1 ChrX:38352483-38421450 (+)
Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to
P00480 (UniProt | EBI)
NM_000531 (RefSeq)
mouse Otc MGI:97448 (MGI)
18416 (Entrez Gene)
Gene Tree
ChrX 4.66 cM ChrX:10252305-10321024 (+)
Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to
OTTMUSG00000016913 (VEGA)
OTTMUSP00000018384 (VEGA)
OTTMUST00000041039 (VEGA)
rat Otc 25611 (Entrez Gene)
ChrX q13 P00481 (UniProt | EBI)
NM_013078 (RefSeq)
cattle OTC 280887 (Entrez Gene)
ChrX Q9N1U7 (UniProt | EBI)
NM_177487 (RefSeq)
dog OTC 480878 (Entrez Gene)
ChrX XP_537995 (RefSeq)
chicken OTC 395735 (Entrez Gene)
Chr1 Q9YHY9 (UniProt | EBI)
NM_204910 (RefSeq)
western clawed frog otc 448273 (Entrez Gene)
ChrUN NP_001005795 (RefSeq)
NM_001005795 (RefSeq)
zebrafish otc 794667 (Entrez Gene)
Chr9 XP_001334671 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory