LPL Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	LPL	HGNC:6677 (HGNC) 4023 (Entrez Gene) 609708 (OMIM) LPL (Alliance of Genome Resources)	Chr8 p21.3	Chr8:19901717-19967259 (+) GRCh38	Alzheimer's disease coronary artery disease familial combined hyperlipidemia familial hyperlipidemia familial lipoprotein lipase deficiency hypertension muscular disease myocardial infarction type 2 diabetes mellitus	P06858 (UniProt \| EBI) NM_000237 (RefSeq)
mouse	Lpl	MGI:96820 (MGI) 16956 (Entrez Gene) Gene Tree Lpl (Alliance of Genome Resources)	Chr8 33.88 cM	Chr8:69333207-69359584 (+) GRCm39	familial lipoprotein lipase deficiency	16956 (NCBI Gene Model) P11152 (UniProt \| EBI) NM_008509 (RefSeq)
rat	Lpl	RGD:3017 (Rat Genome Database) 24539 (Entrez Gene) Lpl (Alliance of Genome Resources)	Chr16 p14			Q06000 (UniProt \| EBI) NM_012598 (RefSeq)
zebrafish	lpla	ZDB-GENE-990415-139 (Zebrafish Model Organism Database) 30354 (Entrez Gene) lpla (Alliance of Genome Resources)	Chr22			NP_571202 (RefSeq) NM_131127 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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