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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ITGB3 HGNC:6156 (HGNC)
3690 (Entrez Gene)
173470 (OMIM)
ITGB3 (Alliance of Genome Resources)
Chr17 q21.32 Chr17:47253827-47313743 (+)
GRCh38
acute myeloid leukemia
asthma
autoimmune thrombocytopenic purpura
blood platelet disease
end stage renal disease
Glanzmann's thrombasthenia
myocardial infarction
non-arteritic anterior ischemic optic neuropathy
platelet-type bleeding disorder 16
thrombocytopenia
P05106 (UniProt | EBI)
NM_000212 (RefSeq)
mouse Itgb3 MGI:96612 (MGI)
16416 (Entrez Gene)
Gene Tree
Itgb3 (Alliance of Genome Resources)
Chr11 67.84 cM Chr11:104498826-104561302 (+)
GRCm39
Glanzmann's thrombasthenia
platelet-type bleeding disorder 16
16416 (NCBI Gene Model)
O54890 (UniProt | EBI)
NM_016780 (RefSeq)
rat Itgb3 RGD:628868 (Rat Genome Database)
29302 (Entrez Gene)
Itgb3 (Alliance of Genome Resources)
Chr10 Q8R2H2 (UniProt | EBI)
NM_153720 (RefSeq)
zebrafish itgb3a ZDB-GENE-071207-1 (Zebrafish Model Organism Database)
564266 (Entrez Gene)
itgb3a (Alliance of Genome Resources)
Chr3 NP_001032312 (RefSeq)
NM_001037235 (RefSeq)
itgb3b ZDB-GENE-071207-2 (Zebrafish Model Organism Database)
100001836 (Entrez Gene)
itgb3b (Alliance of Genome Resources)
Chr12 NP_001076417 (RefSeq)
NM_001082948 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory