GRN Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	GRN	HGNC:4601 (HGNC) 2896 (Entrez Gene) 138945 (OMIM) GRN (Alliance of Genome Resources)	Chr17 q21.31	Chr17:44345246-44353106 (+) GRCh38	Alzheimer's disease amyotrophic lateral sclerosis dementia frontotemporal dementia Grn-related frontotemporal lobar degeneration with Tdp43 inclusions neuronal ceroid lipofuscinosis 11 primary progressive multiple sclerosis	P28799 (UniProt \| EBI) NM_001012479 (RefSeq)
mouse	Grn	MGI:95832 (MGI) 14824 (Entrez Gene) Gene Tree Grn (Alliance of Genome Resources)	Chr11 66.29 cM	Chr11:102321333-102327635 (+) GRCm39	Grn-related frontotemporal lobar degeneration with Tdp43 inclusions nephrogenic diabetes insipidus	14824 (NCBI Gene Model) P28798 (UniProt \| EBI) NM_008175 (RefSeq)
rat	Grn	RGD:61983 (Rat Genome Database) 29143 (Entrez Gene) Grn (Alliance of Genome Resources)	Chr10 q32.1			P23785 (UniProt \| EBI) NM_017113 (RefSeq)
zebrafish	grna	ZDB-GENE-030131-8434 (Zebrafish Model Organism Database) 791524 (Entrez Gene) grna (Alliance of Genome Resources)	Chr3			NP_001001949 (RefSeq) NM_001361234 (RefSeq)
zebrafish	grnb	ZDB-GENE-030131-7393 (Zebrafish Model Organism Database) 335453 (Entrez Gene) grnb (Alliance of Genome Resources)	Chr24			NP_997903 (RefSeq) NM_212738 (RefSeq)