OPA3 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	OPA3	HGNC:8142 (HGNC) 80207 (Entrez Gene) 606580 (OMIM) OPA3 (Alliance of Genome Resources)	Chr19 q13.32	Chr19:45527427-45602212 (-) GRCh38	3-methylglutaconic aciduria type 3 optic atrophy 3	Q9H6K4 (UniProt \| EBI) NM_025136 (RefSeq)
mouse	Opa3	MGI:2686271 (MGI) 403187 (Entrez Gene) Gene Tree Opa3 (Alliance of Genome Resources)	Chr7 9.48 cM	Chr7:18962314-18980742 (+) GRCm39	3-methylglutaconic aciduria type 3	403187 (NCBI Gene Model) Q505D7 (UniProt \| EBI) NM_207525 (RefSeq)
zebrafish	opa3	ZDB-GENE-050210-1 (Zebrafish Model Organism Database) 497278 (Entrez Gene) opa3 (Alliance of Genome Resources)	Chr18			Q1L9A2 (UniProt \| EBI) NM_001080166 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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