HTRA2 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	HTRA2	HGNC:14348 (HGNC) 27429 (Entrez Gene) 606441 (OMIM) HTRA2 (Alliance of Genome Resources)	Chr2 p13.1	Chr2:74529405-74533556 (+) GRCh38	3-methylglutaconic aciduria type 8 motor neuron disease Parkinson's disease	O43464 (UniProt \| EBI) NM_145074 (RefSeq)
mouse	Htra2	MGI:1928676 (MGI) 64704 (Entrez Gene) Gene Tree Htra2 (Alliance of Genome Resources)	Chr6 35.94 cM	Chr6:83028247-83031552 (-) GRCm39		64704 (NCBI Gene Model) Q9JIY5 (UniProt \| EBI) NM_019752 (RefSeq)
rat	Htra2	RGD:1308906 (Rat Genome Database) 297376 (Entrez Gene) Htra2 (Alliance of Genome Resources)	Chr4 q34			NP_001100069 (RefSeq) NM_001106599 (RefSeq)
zebrafish	htra2-4	ZDB-GENE-081028-23 (Zebrafish Model Organism Database) 797876 (Entrez Gene) htra2-4 (Alliance of Genome Resources)	Chr13			XP_021336616 (RefSeq)
	htra2-7	ZDB-GENE-081028-27 (Zebrafish Model Organism Database) 799791 (Entrez Gene) htra2-7 (Alliance of Genome Resources)	Chr13			XP_017214429 (RefSeq)
	htra2-8	ZDB-GENE-081028-29 (Zebrafish Model Organism Database) 560704 (Entrez Gene) htra2-8 (Alliance of Genome Resources)	Chr13
	htra2-10	ZDB-GENE-081028-17 (Zebrafish Model Organism Database) 100003428 (Entrez Gene) htra2-10 (Alliance of Genome Resources)	Chr13			NP_001098612 (RefSeq) NM_001105142 (RefSeq)
	htra2-14	ZDB-GENE-080215-8 (Zebrafish Model Organism Database) 100137109 (Entrez Gene) htra2-14 (Alliance of Genome Resources)	Chr13			NP_001108178 (RefSeq) NM_001114706 (RefSeq)
	si:busm1-sl7.7	ZDB-GENE-041001-38 (Zebrafish Model Organism Database) 100034638 (Entrez Gene) si:busm1-sl7.7 (Alliance of Genome Resources)	Chr13			XP_021328327 (RefSeq)
	si:dkey-10b15.8	ZDB-GENE-141212-238 (Zebrafish Model Organism Database) 560031 (Entrez Gene) si:dkey-10b15.8 (Alliance of Genome Resources)	Chr10			XP_017213555 (RefSeq)
	si:dkey-33c12.12	ZDB-GENE-081028-30 (Zebrafish Model Organism Database) 100000024 (Entrez Gene) si:dkey-33c12.12 (Alliance of Genome Resources)	Chr13			NP_001082916 (RefSeq) NM_001089447 (RefSeq)
	si:dkey-84o3.2	ZDB-GENE-091113-19 (Zebrafish Model Organism Database) 100330919 (Entrez Gene) si:dkey-84o3.2 (Alliance of Genome Resources)	Chr21			XP_005161042 (RefSeq)
	si:dkey-84o3.7	ZDB-GENE-091113-30 (Zebrafish Model Organism Database) 799634 (Entrez Gene) si:dkey-84o3.7 (Alliance of Genome Resources)	Chr21			XP_017208436 (RefSeq)
	si:dkey-112g5.13	ZDB-GENE-081028-21 (Zebrafish Model Organism Database) 100003308 (Entrez Gene) si:dkey-112g5.13 (Alliance of Genome Resources)	Chr13			NP_001103205 (RefSeq) NM_001109735 (RefSeq)
	si:dkey-112g5.16	ZDB-GENE-141219-11 (Zebrafish Model Organism Database) 799537 (Entrez Gene) si:dkey-112g5.16 (Alliance of Genome Resources)	Chr13			NP_001103640 (RefSeq) NM_001110170 (RefSeq)