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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HTRA2 HGNC:14348 (HGNC)
27429 (Entrez Gene)
606441 (OMIM)
HtrA serine peptidase 2 (MyGene.info)
HGNC homology
Chr2 p13.1 Chr2:74529405-74533556 (+)
Parkinson's disease
O43464 (UniProt | EBI)
NM_001321727 (RefSeq)
mouse Htra2 MGI:1928676 (MGI)
64704 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 35.94 cM Chr6:83051266-83055273 (-)
OTTMUSG00000022486 (VEGA)
OTTMUSP00000025609 (VEGA)
OTTMUST00000053814 (VEGA)
rat Htra2 297376 (Entrez Gene)
Chr4 q34 NP_001100069 (RefSeq)
NM_001106599 (RefSeq)
chimpanzee HTRA2 459339 (Entrez Gene)
Chr2A NP_001267074 (RefSeq)
NM_001280145 (RefSeq)
cattle HTRA2 523039 (Entrez Gene)
Chr11 A0JNK3 (UniProt | EBI)
NM_001077956 (RefSeq)
dog HTRA2 475782 (Entrez Gene)
Chr17 NP_001271389 (RefSeq)
NM_001284460 (RefSeq)
chicken HTRA2 395990 (Entrez Gene)
Chr4 XP_015156781 (RefSeq)
zebrafish LOC560917 560917 (Entrez Gene)
Chr10 XP_021335194 (RefSeq)
LOC793110 793110 (Entrez Gene)
Chr10 XP_021335094 (RefSeq)
LOC793521 793521 (Entrez Gene)
Chr10 XP_021335097 (RefSeq)
LOC797799 797799 (Entrez Gene)
Chr13 NP_001103998 (RefSeq)
NM_001110528 (RefSeq)
LOC799006 799006 (Entrez Gene)
Chr13 XP_021328345 (RefSeq)
LOC100149563 100149563 (Entrez Gene)
Chr13 NP_001122292 (RefSeq)
NM_001128820 (RefSeq)
LOC100329860 100329860 (Entrez Gene)
LOC100331049 100331049 (Entrez Gene)
Chr21 XP_002665901 (RefSeq)
si:busm1-sl7.7 100034638 (Entrez Gene)
Chr13 XP_021328327 (RefSeq)
si:dkey-19p15.4 100536969 (Entrez Gene)
si:dkey-19p15.4 797876 (Entrez Gene)
Chr13 XP_021336616 (RefSeq)
si:dkey-33c12.2 560031 (Entrez Gene)
Chr10 XP_021328013 (RefSeq)
si:dkey-33c12.10 799791 (Entrez Gene)
Chr13 XP_021336411 (RefSeq)
si:dkey-84o3.2 100330919 (Entrez Gene)
Chr21 XP_021324645 (RefSeq)
si:dkey-84o3.3 100149280 (Entrez Gene)
si:dkey-84o3.7 799634 (Entrez Gene)
Chr21 XP_017208436 (RefSeq)
si:dkey-112g5.13 100003308 (Entrez Gene)
Chr13 NP_001103205 (RefSeq)
NM_001109735 (RefSeq)
si:dkey-112g5.16 799537 (Entrez Gene)
Chr13 NP_001103640 (RefSeq)
NM_001110170 (RefSeq)
zgc:173425 100003428 (Entrez Gene)
Chr13 NP_001098612 (RefSeq)
NM_001105142 (RefSeq)
zgc:174193 100137109 (Entrez Gene)
Chr13 NP_001108178 (RefSeq)
NM_001114706 (RefSeq)
macaque, rhesus HTRA2 709938 (Entrez Gene)
Chr13 NP_001245067 (RefSeq)
NM_001258138 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory