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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIRT2 HGNC:10886 (HGNC)
22933 (Entrez Gene)
604480 (OMIM)
SIRT2 (MyGene.info)
HGNC homology
Chr19 q13.2 Chr19:38878555-38899862 (-)
Q8IXJ6 (UniProt | EBI)
NM_030593 (RefSeq)
mouse Sirt2 MGI:1927664 (MGI)
64383 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 16.92 cM Chr7:28766735-28788661 (+)
OTTMUSG00000017294 (VEGA)
OTTMUSP00000018858 (VEGA)
OTTMUST00000041937 (VEGA)
rat Sirt2 361532 (Entrez Gene)
Chr1 q21 Q5RJQ4 (UniProt | EBI)
NM_001008368 (RefSeq)
chimpanzee SIRT2 456013 (Entrez Gene)
Chr19 NP_001267084 (RefSeq)
NM_001280155 (RefSeq)
cattle SIRT2 504463 (Entrez Gene)
Chr18 NP_001107003 (RefSeq)
NM_001113531 (RefSeq)
dog SIRT2 612558 (Entrez Gene)
Chr1 XP_013976051 (RefSeq)
chicken SIRT2 548628 (Entrez Gene)
Chr32 NP_001017414 (RefSeq)
NM_001017414 (RefSeq)
zebrafish sirt2 322309 (Entrez Gene)
Chr15 Q7ZVK3 (UniProt | EBI)
NM_199596 (RefSeq)
frog, western clawed sirt2 100489469 (Entrez Gene)
Chr2 XP_004910775 (RefSeq)
macaque, rhesus SIRT2 100425019 (Entrez Gene)
Chr19 XP_014979357 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory