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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CASP4 HGNC:1505 (HGNC)
837 (Entrez Gene)
602664 (OMIM)
HGNC homology
Chr11 q22.3 Chr11:104942866-104968598 (-)
P49662 (UniProt | EBI)
NM_001225 (RefSeq)
mouse Casp4 MGI:107700 (MGI)
12363 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 2.46 cM Chr9:5308828-5336783 (+)
OTTMUSG00000033830 (VEGA)
OTTMUSP00000046015 (VEGA)
OTTMUST00000085221 (VEGA)
rat Casp4 114555 (Entrez Gene)
Chr8 q11 NP_446188 (RefSeq)
NM_053736 (RefSeq)
chimpanzee CASP4 451518 (Entrez Gene)
Chr11 XP_009422361 (RefSeq)
cattle CASP4 338039 (Entrez Gene)
Chr15 Q5E9C1 (UniProt | EBI)
NM_176638 (RefSeq)
macaque, rhesus CASP4 704864 (Entrez Gene)
Chr14 NP_001247885 (RefSeq)
NM_001260956 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory