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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1746

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LRP5 HGNC:6697 (HGNC)
4041 (Entrez Gene)
603506 (OMIM)
Chr11 q13.4 Chr11:68312609-68449275 (+)
GRCh38
Exudative Vitreoretinopathy 1; EVR1
Exudative Vitreoretinopathy 4; EVR4
Hyperostosis Corticalis Generalisata, Benign Form of Worth, with Torus Palatinus
Osteopetrosis, Autosomal Dominant 1; OPTA1
Osteoporosis
Osteoporosis-Pseudoglioma Syndrome; OPPG
Van Buchem Disease, Type 2
O75197 (UniProt | EBI)
NM_002335 (RefSeq)
mouse Lrp5 MGI:1278315 (MGI)
16973 (Entrez Gene)
Gene Tree
VISTA-Point
Chr19 3.33 cM Chr19:3584828-3686564 (-)
GRCm38
Exudative Vitreoretinopathy 4; EVR4
Osteoporosis-Pseudoglioma Syndrome; OPPG
OTTMUSG00000042195 (VEGA)
OTTMUSP00000061850 (VEGA)
OTTMUST00000110769 (VEGA)
rat Lrp5 293649 (Entrez Gene)
Chr1 q42 NP_001099791 (RefSeq)
NM_001106321 (RefSeq)
chimpanzee LRP5 451380 (Entrez Gene)
Chr11 XP_508605 (RefSeq)
cattle LRP5 534450 (Entrez Gene)
Chr29 XP_614220 (RefSeq)
dog LRP5 100306933 (Entrez Gene)
Chr18 XP_003432463 (RefSeq)
chicken LRP5 423114 (Entrez Gene)
Chr5 NP_001012915 (RefSeq)
NM_001012897 (RefSeq)
western clawed frog lrp5 100491803 (Entrez Gene)
ChrUN XP_002941689 (RefSeq)
zebrafish lrp5 568518 (Entrez Gene)
Chr25 NP_001170929 (RefSeq)
NM_001177458 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory