LRP5 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	LRP5	HGNC:6697 (HGNC) 4041 (Entrez Gene) 603506 (OMIM) LRP5 (Alliance of Genome Resources)	Chr11 q13.2	Chr11:68298412-68449275 (+) GRCh38	autosomal dominant osteopetrosis 1 autosomal dominant polycystic kidney disease exudative vitreoretinopathy 4 idiopathic juvenile osteoporosis microphthalmia neovascular inflammatory vitreoretinopathy osteoporosis osteoporosis-pseudoglioma syndrome polycystic liver disease Worth syndrome	O75197 (UniProt \| EBI) NM_001291902 (RefSeq)
human	LRP5L	HGNC:25323 (HGNC) 91355 (Entrez Gene) LRP5L (Alliance of Genome Resources)	Chr22 q11.23	Chr22:25351418-25405408 (-) GRCh38		A4QPB2 (UniProt \| EBI) NM_001135772 (RefSeq)
mouse	Lrp5	MGI:1278315 (MGI) 16973 (Entrez Gene) Gene Tree Lrp5 (Alliance of Genome Resources)	Chr19 3.33 cM	Chr19:3634828-3736564 (-) GRCm39	exudative vitreoretinopathy osteoporosis-pseudoglioma syndrome	ENSMUSG00000024913 (Ensembl Gene Model) ENSMUSP00000025856 (Ensembl) ENSMUST00000025856 (Ensembl)
rat	Lrp5	RGD:1309329 (Rat Genome Database) 293649 (Entrez Gene) Lrp5 (Alliance of Genome Resources)	Chr1 q42-q43			NP_001099791 (RefSeq) NM_001106321 (RefSeq)
zebrafish	lrp5	ZDB-GENE-050518-2 (Zebrafish Model Organism Database) 568518 (Entrez Gene) lrp5 (Alliance of Genome Resources)	Chr25			NP_001170929 (RefSeq) NM_001177458 (RefSeq)