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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human E4F1 HGNC:3121 (HGNC)
1877 (Entrez Gene)
603022 (OMIM)
E4F1 (MyGene.info)
HGNC homology
Chr16 p13.3 Chr16:2223488-2235742 (+)
Q66K89 (UniProt | EBI)
NM_001288778 (RefSeq)
mouse E4f1 MGI:109530 (MGI)
13560 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 12.39 cM Chr17:24443778-24455392 (-)
13560 (NCBI Gene Model)
Q8CCE9 (UniProt | EBI)
NM_001301784 (RefSeq)
rat E4f1 681359 (Entrez Gene)
Chr10 q12 NP_001171975 (RefSeq)
NM_001185046 (RefSeq)
chimpanzee E4F1 454356 (Entrez Gene)
Chr16 XP_016784123 (RefSeq)
cattle E4F1 515997 (Entrez Gene)
Chr25 NP_001192754 (RefSeq)
NM_001205825 (RefSeq)
dog E4F1 100683433 (Entrez Gene)
Chr6 XP_013969913 (RefSeq)
chicken E4F1 416560 (Entrez Gene)
Chr14 XP_015149958 (RefSeq)
zebrafish e4f1 561158 (Entrez Gene)
Chr3 Q4V8R6 (UniProt | EBI)
NM_001025513 (RefSeq)
frog, western clawed e4f1 548399 (Entrez Gene)
Chr9 NP_001072166 (RefSeq)
NM_001078698 (RefSeq)
macaque, rhesus E4F1 695882 (Entrez Gene)
Chr20 NP_001252626 (RefSeq)
NM_001265697 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory