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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PDX1 HGNC:6107 (HGNC)
3651 (Entrez Gene)
600733 (OMIM)
PDX1 (MyGene.info)
HGNC homology
Chr13 q12.2 Chr13:27919982-27926314 (+)
maturity-onset diabetes of the young type 4
pancreatic agenesis
permanent neonatal diabetes mellitus
type 2 diabetes mellitus
P52945 (UniProt | EBI)
NM_000209 (RefSeq)
mouse Pdx1 MGI:102851 (MGI)
18609 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 86.84 cM Chr5:147270131-147275149 (+)
maturity-onset diabetes of the young
maturity-onset diabetes of the young type 4
type 1 diabetes mellitus
18609 (NCBI Gene Model)
P52946 (UniProt | EBI)
NM_008814 (RefSeq)
rat Pdx1 29535 (Entrez Gene)
Chr12 P52947 (UniProt | EBI)
NM_022852 (RefSeq)
chimpanzee PDX1 452507 (Entrez Gene)
Chr13 A2T756 (UniProt | EBI)
NM_001081478 (RefSeq)
cattle PDX1 538927 (Entrez Gene)
Chr12 NP_001179065 (RefSeq)
NM_001192136 (RefSeq)
dog PDX1 493994 (Entrez Gene)
Chr25 NP_001271400 (RefSeq)
NM_001284471 (RefSeq)
chicken PDX1 771348 (Entrez Gene)
Chr1 XP_001234636 (RefSeq)
zebrafish pdx1 30721 (Entrez Gene)
Chr24 NP_571518 (RefSeq)
NM_131443 (RefSeq)
frog, western clawed pdx1 100490648 (Entrez Gene)
Chr2 XP_002934065 (RefSeq)
macaque, rhesus PDX1 710936 (Entrez Gene)
Chr17 XP_001096758 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory