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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SOX2 HGNC:11195 (HGNC)
6657 (Entrez Gene)
184429 (OMIM)
SOX2 (MyGene.info)
HGNC homology
Chr3 q26.33 Chr3:181711924-181714436 (+)
syndromic microphthalmia 3
P48431 (UniProt | EBI)
NM_003106 (RefSeq)
mouse Sox2 MGI:98364 (MGI)
20674 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 16.93 cM Chr3:34650405-34652461 (+)
ENSMUSG00000074637 (Ensembl Gene Model)
ENSMUSP00000096755 (Ensembl)
ENSMUST00000099151 (Ensembl)
rat Sox2 499593 (Entrez Gene)
Chr2 q24 NP_001102651 (RefSeq)
NM_001109181 (RefSeq)
chimpanzee SOX2 460869 (Entrez Gene)
Chr3 XP_516895 (RefSeq)
cattle SOX2 784383 (Entrez Gene)
Chr1 q33 NP_001098933 (RefSeq)
NM_001105463 (RefSeq)
dog SOX2 488092 (Entrez Gene)
Chr34 XP_005639809 (RefSeq)
chicken SOX2 396105 (Entrez Gene)
Chr9 P48430 (UniProt | EBI)
NM_205188 (RefSeq)
zebrafish sox2 378723 (Entrez Gene)
Chr22 Q6P0E1 (UniProt | EBI)
NM_213118 (RefSeq)
frog, western clawed sox2 407873 (Entrez Gene)
Chr5 Q6NVN0 (UniProt | EBI)
NM_213704 (RefSeq)
macaque, rhesus SOX2 707039 (Entrez Gene)
Chr2 NP_001136412 (RefSeq)
NM_001142940 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory