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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CTSD HGNC:2529 (HGNC)
1509 (Entrez Gene)
116840 (OMIM)
Cathepsin D (MyGene.info)
HGNC homology
Chr11 p15.5 Chr11:1752752-1763992 (-)
neuronal ceroid lipofuscinosis 10
P07339 (UniProt | EBI)
NM_001909 (RefSeq)
mouse Ctsd MGI:88562 (MGI)
13033 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 87.93 cM Chr7:142375916-142387870 (-)
neuronal ceroid lipofuscinosis 10
13033 (NCBI Gene Model)
P18242 (UniProt | EBI)
NM_009983 (RefSeq)
rat Ctsd 171293 (Entrez Gene)
Chr1 q41 P24268 (UniProt | EBI)
NM_134334 (RefSeq)
cattle CTSD 282883 (Entrez Gene)
Chr29 P80209 (UniProt | EBI)
NM_001166521 (RefSeq)
dog CTSD 483662 (Entrez Gene)
Chr18 Q4LAL9 (UniProt | EBI)
NM_001025621 (RefSeq)
chicken CTSD 396090 (Entrez Gene)
Chr5 Q05744 (UniProt | EBI)
NM_205177 (RefSeq)
zebrafish ctsd 65225 (Entrez Gene)
Chr18 NP_571785 (RefSeq)
NM_131710 (RefSeq)
frog, western clawed ctsd 394561 (Entrez Gene)
Chr4 NP_988964 (RefSeq)
NM_203633 (RefSeq)
LOC613063 613063 (Entrez Gene)
Chr4 NP_001136375 (RefSeq)
NM_001142903 (RefSeq)
LOC100489529 100489529 (Entrez Gene)
ChrUN XP_012810674 (RefSeq)
LOC101735147 101735147 (Entrez Gene)
Chr4 XP_017948612 (RefSeq)
macaque, rhesus CTSD 703534 (Entrez Gene)
Chr20 NP_001247483 (RefSeq)
NM_001260554 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory