Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CANT1
  • Mouse genes Cant1
  • Rat genes Cant1
  • Zfish genes cant1a,cant1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cant1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043262	ADP phosphatase activity	CANT1	IDA		Human	PMID:16835225
Molecular Function	GO:0005509	calcium ion binding	CANT1	IDA		Human	PMID:16835225
Molecular Function	GO:0004382	GDP phosphatase activity	CANT1	IDA		Human	PMID:16835225
Molecular Function	GO:0005515	protein binding	CANT1	IPI	UniProtKB:P58418	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CANT1	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	CANT1	IDA		Human	PMID:16835225
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Cant1	IDA		Rat	PMID:12167635|RGD:631908
Cellular Component	GO:0070062	extracellular exosome	CANT1	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	CANT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	CANT1	IDA		Human	PMID:16835225
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	CANT1	HMP		Human	PMID:12761501
Biological Process	GO:0030166	proteoglycan biosynthetic process	CANT1	IMP		Human	PMID:22539336

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern