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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
88807

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:88807

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:88807
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0031698beta-2 adrenergic receptor bindingNEDD4IDAHumanPMID:18544533
Molecular FunctionGO:0050815phosphoserine bindingNedd4IDAMouseMGI:MGI:3813439|PMID:10037602
Molecular FunctionGO:0050816phosphothreonine bindingNedd4IDAMouseMGI:MGI:3813439|PMID:10037602
Molecular FunctionGO:0070064proline-rich region bindingNEDD4IPIUniProtKB:Q15038HumanPMID:11342538
Molecular FunctionGO:0070064proline-rich region bindingNEDD4IMPHumanPMID:15126635
Molecular FunctionGO:0070064proline-rich region bindingNedd4IPIUniProtKB:Q8R0W6MouseMGI:MGI:2176314|PMID:11748237
Molecular FunctionGO:0070064proline-rich region bindingNedd4IPIUniProtKB:P97764|UniProtKB:Q16621MouseMGI:MGI:3814925|PMID:9305852
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P37088HumanPMID:10642508
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P51168HumanPMID:10642508
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P51170HumanPMID:10642508
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q9Y4G8HumanPMID:11598133
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q9NV92HumanPMID:12796489
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q9Y3C5HumanPMID:15231748
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q99732HumanPMID:16118794
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P05161HumanPMID:18305167
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P60484HumanPMID:19345329
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:O54967HumanPMID:20086093
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P10114HumanPMID:20159449
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q9UKE5HumanPMID:20159449
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:O95166HumanPMID:20562859
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P60520HumanPMID:20562859
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q9H0R8HumanPMID:20562859
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q9Y3C5HumanPMID:20676133
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P11362HumanPMID:21765395
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P51168HumanPMID:21765395
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:Q16621HumanPMID:9305852
Molecular FunctionGO:0005515protein bindingNEDD4IPIUniProtKB:P68036HumanPMID:9990509
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:Q60760MouseMGI:MGI:1342855|PMID:10446181
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:Q8R0W6MouseMGI:MGI:1927025|PMID:11042109
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:Q9EQG5MouseMGI:MGI:1927025|PMID:11042109
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:Q99MK8MouseMGI:MGI:3713955|PMID:17544362
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:Q9WU38MouseMGI:MGI:3713955|PMID:17544362
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:Q13322MouseMGI:MGI:4441129|PMID:15060076
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:Q8C7U1|UniProtKB:Q6A037|UniProtKB:F8VQG7MouseMGI:MGI:4835039|PMID:11717310
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:P83510|UniProtKB:Q80ZJ1MouseMGI:MGI:4835109|PMID:20159449
Molecular FunctionGO:0005515protein bindingNedd4IPIUniProtKB:P70175MouseMGI:MGI:5299396|PMID:21920314
Molecular FunctionGO:0005515protein bindingNedd4IPIRGD:3640RatRGD:1642065|PMID:11527431
Molecular FunctionGO:0005515protein bindingNedd4IPIRGD:3641RatRGD:1642065|PMID:11527431
Molecular FunctionGO:0008022protein C-terminus bindingNedd4IDARatRGD:2301360|PMID:9923703
Molecular FunctionGO:0008022protein C-terminus bindingNedd4IPIRGD:3639|RGD:3640|RGD:3641RatRGD:633483|PMID:8665844
Molecular FunctionGO:0019904protein domain specific bindingNEDD4IPIUniProtKB:Q969W9HumanPMID:12907594
Molecular FunctionGO:0070063RNA polymerase bindingNEDD4IPIUniProtKB:P24928HumanPMID:17996703
Molecular FunctionGO:0019871sodium channel inhibitor activityNEDD4IDAHumanPMID:10642508
Molecular FunctionGO:0019871sodium channel inhibitor activityNedd4IDAMouseMGI:MGI:1336453|PMID:10212229
Molecular FunctionGO:0043130ubiquitin bindingNEDD4IDAHumanPMID:9990509
Molecular FunctionGO:0004842ubiquitin-protein ligase activityNEDD4IDAHumanPMID:17996703
Molecular FunctionGO:0004842ubiquitin-protein ligase activityNEDD4IDAHumanPMID:20086093
Molecular FunctionGO:0004842ubiquitin-protein ligase activityNedd4IDAMouseMGI:MGI:892833|PMID:9182527
Molecular FunctionGO:0004842ubiquitin-protein ligase activityNedd4IDAMouseMGI:MGI:4835039|PMID:11717310
Molecular FunctionGO:0004842ubiquitin-protein ligase activityNedd4IDARatPMID:20159449
Molecular FunctionGO:0004842ubiquitin-protein ligase activityNedd4IDARatPMID:20159449
Cellular ComponentGO:0005938cell cortexNEDD4IDAHumanPMID:9990509
Cellular ComponentGO:0000785chromatinNEDD4IDAHumanPMID:17996703
Cellular ComponentGO:0005737cytoplasmNEDD4IDAHumanPMID:12796489
Cellular ComponentGO:0005737cytoplasmNedd4IDAMouseMGI:MGI:3038342|PMID:14973438
Cellular ComponentGO:0005829cytosolNedd4IDAMouseMGI:MGI:892833|PMID:9182527
Cellular ComponentGO:0005829cytosolNedd4IDAMouseMGI:MGI:4830839|PMID:19794060
Cellular ComponentGO:0005794Golgi apparatusNEDD4IDAHumanPMID:16118794
Cellular ComponentGO:0016020membraneNedd4IDAMouseMGI:MGI:3038342|PMID:14973438
Cellular ComponentGO:0045121membrane raftNedd4IDARatRGD:1642066|PMID:11248052
Cellular ComponentGO:0005902microvillusNedd4IDARatRGD:1642067|PMID:9227416
Cellular ComponentGO:0048471perinuclear region of cytoplasmNEDD4IDAHumanPMID:9990509
Cellular ComponentGO:0005886plasma membraneNEDD4IMPHumanPMID:15126635
Cellular ComponentGO:0005886plasma membraneNEDD4IDAHumanPMID:16118794
Cellular ComponentGO:0000151ubiquitin ligase complexNedd4IPIUniProtKB:Q9QYK7MouseMGI:MGI:1927025|PMID:11042109
Biological ProcessGO:0002250adaptive immune responseNedd4IMPMGI:MGI:3829272MouseMGI:MGI:3828188|PMID:18931680
Biological ProcessGO:0048514blood vessel morphogenesisNedd4IMPMGI:MGI:3799317MouseMGI:MGI:4452597|PMID:20026598
Biological ProcessGO:0048514blood vessel morphogenesisNedd4IGIMGI:MGI:98737MouseMGI:MGI:4452597|PMID:20026598
Biological ProcessGO:0034644cellular response to UVNEDD4IMPHumanPMID:17996703
Biological ProcessGO:0044111development involved in symbiotic interactionNEDD4IMPHumanPMID:15126635
Biological ProcessGO:0003197endocardial cushion developmentNedd4IMPMGI:MGI:3799317MouseMGI:MGI:4452597|PMID:20026598
Biological ProcessGO:0003197endocardial cushion developmentNedd4IGIMGI:MGI:98737MouseMGI:MGI:4452597|PMID:20026598
Biological ProcessGO:0042921glucocorticoid receptor signaling pathwayNEDD4IDAHumanPMID:8649367
Biological ProcessGO:0007041lysosomal transportNEDD4IDAHumanPMID:18544533
Biological ProcessGO:0010766negative regulation of sodium ion transportNEDD4IDAHumanPMID:10642508
Biological ProcessGO:0010766negative regulation of sodium ion transportNedd4IDAMouseMGI:MGI:1336453|PMID:10212229
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterNedd4IMPMGI:MGI:3799317MouseMGI:MGI:4452597|PMID:20026598
Biological ProcessGO:0010768negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damageNEDD4IMPHumanPMID:17996703
Biological ProcessGO:0030948negative regulation of vascular endothelial growth factor receptor signaling pathwayNedd4IDAMouseMGI:MGI:4441129|PMID:15060076
Biological ProcessGO:0007528neuromuscular junction developmentNedd4IMPMGI:MGI:3529811MouseMGI:MGI:3848079|PMID:19345204
Biological ProcessGO:0003151outflow tract morphogenesisNedd4IMPMGI:MGI:3799317MouseMGI:MGI:4452597|PMID:20026598
Biological ProcessGO:0003151outflow tract morphogenesisNedd4IGIMGI:MGI:98737MouseMGI:MGI:4452597|PMID:20026598
Biological ProcessGO:0046824positive regulation of nucleocytoplasmic transportNEDD4IDAHumanPMID:17218261
Biological ProcessGO:0014068positive regulation of phosphatidylinositol 3-kinase signalingNEDD4IMPHumanPMID:17218260
Biological ProcessGO:0045732positive regulation of protein catabolic processNEDD4IDAHumanPMID:14973438
Biological ProcessGO:0045732positive regulation of protein catabolic processNedd4IDAMouseMGI:MGI:2176314|PMID:11748237
Biological ProcessGO:0050847progesterone receptor signaling pathwayNEDD4IDAHumanPMID:8649367
Biological ProcessGO:0070534protein K63-linked ubiquitinationNedd4IDARatPMID:20159449
Biological ProcessGO:0070534protein K63-linked ubiquitinationNedd4IDARatPMID:20159449
Biological ProcessGO:0006513protein monoubiquitinationNedd4IDAMouseMGI:MGI:5299396|PMID:21920314
Biological ProcessGO:0006622protein targeting to lysosomeNEDD4IDAHumanPMID:17116753
Biological ProcessGO:0016567protein ubiquitinationNEDD4IDAHumanPMID:18305167
Biological ProcessGO:0016567protein ubiquitinationNedd4IDAMouseMGI:MGI:892833|PMID:9182527
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processNEDD4IMPHumanPMID:17218260
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processNEDD4IMPHumanPMID:17996703
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processNEDD4IDAHumanPMID:20086093
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processNedd4IMPMGI:MGI:3829272MouseMGI:MGI:3828188|PMID:18931680
Biological ProcessGO:0032801receptor catabolic processNEDD4IDAHumanPMID:18544533
Biological ProcessGO:0031623receptor internalizationNEDD4IDAHumanPMID:18544533
Biological ProcessGO:0048814regulation of dendrite morphogenesisNedd4IMPMouseMGI:MGI:4835109|PMID:20159449
Biological ProcessGO:0048814regulation of dendrite morphogenesisNedd4IDARatPMID:20159449
Biological ProcessGO:0048814regulation of dendrite morphogenesisNedd4IDARatPMID:20159449
Biological ProcessGO:0034765regulation of ion transmembrane transportNEDD4IDAHumanPMID:17289006
Biological ProcessGO:0042391regulation of membrane potentialNEDD4IDAHumanPMID:17289006
Biological ProcessGO:1901016regulation of potassium ion transmembrane transporter activityNEDD4IDAHumanPMID:17289006
Biological ProcessGO:0050807regulation of synapse organizationNedd4IMPMGI:MGI:3529811MouseMGI:MGI:3848079|PMID:19345204
Biological ProcessGO:0042110T cell activationNedd4IMPMGI:MGI:3829272MouseMGI:MGI:3828188|PMID:18931680
Biological ProcessGO:0019089transmission of virusNEDD4IMPHumanPMID:15126635
Biological ProcessGO:0043162ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathwayNEDD4IMPHumanPMID:20086093

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory