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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
88442

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:88442

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:88442
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0045236CXCR chemokine receptor bindingITCHIPIUniProtKB:P61073HumanPMID:19116316
Molecular FunctionGO:0016874ligase activityItchIMPMouseMGI:MGI:3774677|PMID:18246070
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:O15350-1HumanPMID:15678106
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:O15350-8HumanPMID:15678106
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q96BR1HumanPMID:16888620
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q86Y01HumanPMID:17028573
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:P13285HumanPMID:17174309
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q6A037HumanPMID:17592138
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q8N0X7HumanPMID:19580544
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q9H3M7HumanPMID:20068034
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:P70444HumanPMID:20392206
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q9Y5X1HumanPMID:20491914
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q9Y3C5HumanPMID:20676133
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:P08151HumanPMID:20818436
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q9QZS3-2HumanPMID:20818436
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q15303HumanPMID:20858735
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q9NQC7HumanPMID:22057290
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:Q9BTU6HumanPMID:23146885
Molecular FunctionGO:0005515protein bindingITCHIPIUniProtKB:P54259HumanPMID:9647693
Molecular FunctionGO:0005515protein bindingItchIPIUniProtKB:Q61146MouseMGI:MGI:2176656|PMID:11782481
Molecular FunctionGO:0005515protein bindingItchIPIUniProtKB:Q8R0W6MouseMGI:MGI:3694584|PMID:17137798
Molecular FunctionGO:0005515protein bindingItchIPIUniProtKB:Q3UKC1MouseMGI:MGI:3774677|PMID:18246070
Molecular FunctionGO:0005515protein bindingItchIPIUniProtKB:Q80TQ2MouseMGI:MGI:5300860|PMID:22057290
Molecular FunctionGO:0005515protein bindingItchIPIUniProtKB:Q2TBE6RatPMID:23146885
Molecular FunctionGO:0005515protein bindingItchIPIUniProtKB:Q2TBE6RatPMID:23146885
Molecular FunctionGO:0043021ribonucleoprotein complex bindingITCHIPIUniProtKB:Q15366HumanPMID:19881509
Molecular FunctionGO:0004842ubiquitin-protein ligase activityITCHIDAHumanPMID:15678106
Molecular FunctionGO:0004842ubiquitin-protein ligase activityITCHIDAHumanPMID:17592138
Cellular ComponentGO:0005938cell cortexItchIDAMouseMGI:MGI:3694584|PMID:17137798
Cellular ComponentGO:0005737cytoplasmITCHIDAHumanGO_REF:0000052
Cellular ComponentGO:0005737cytoplasmItchIDAMouseMGI:MGI:3038342|PMID:14973438
Cellular ComponentGO:0031410cytoplasmic vesicleItchIDAMouseMGI:MGI:3694584|PMID:17137798
Cellular ComponentGO:0016020membraneItchIDAMouseMGI:MGI:3038342|PMID:14973438
Cellular ComponentGO:0005634nucleusItchIDAMouseMGI:MGI:2150845|PMID:11555636
Cellular ComponentGO:0005886plasma membraneITCHIDAHumanPMID:14602072
Biological ProcessGO:0046642negative regulation of alpha-beta T cell proliferationItchIMPMGI:MGI:1856404MouseMGI:MGI:3038342|PMID:14973438
Biological ProcessGO:0043066negative regulation of apoptotic processITCHIMPHumanPMID:20068034
Biological ProcessGO:0050687negative regulation of defense response to virusITCHIMPHumanPMID:19881509
Biological ProcessGO:0050687negative regulation of defense response to virusItchIMPMouseMGI:MGI:4436832|PMID:19881509
Biological ProcessGO:0046329negative regulation of JNK cascadeItchIMPMouseMGI:MGI:3774677|PMID:18246070
Biological ProcessGO:0032088negative regulation of NF-kappaB transcription factor activityItchIMPMouseMGI:MGI:3774677|PMID:18246070
Biological ProcessGO:0045732positive regulation of protein catabolic processItchIMPMGI:MGI:1856404MouseMGI:MGI:3038342|PMID:14973438
Biological ProcessGO:0045732positive regulation of protein catabolic processItchIDAMouseMGI:MGI:3038342|PMID:14973438
Biological ProcessGO:0002669positive regulation of T cell anergyItchIMPMGI:MGI:1856404MouseMGI:MGI:3038342|PMID:14973438
Biological ProcessGO:0035519protein K29-linked ubiquitinationITCHIDAHumanPMID:17028573
Biological ProcessGO:0035519protein K29-linked ubiquitinationITCHIDAHumanPMID:18628966
Biological ProcessGO:0070936protein K48-linked ubiquitinationITCHIDAHumanPMID:19881509
Biological ProcessGO:0070936protein K48-linked ubiquitinationItchIMPMouseMGI:MGI:3774677|PMID:18246070
Biological ProcessGO:0070534protein K63-linked ubiquitinationITCHIDAHumanPMID:18718448
Biological ProcessGO:0070534protein K63-linked ubiquitinationITCHIDAHumanPMID:19592251
Biological ProcessGO:0000209protein polyubiquitinationItchIDAMouseMGI:MGI:3038342|PMID:14973438
Biological ProcessGO:0016567protein ubiquitinationITCHIDAHumanPMID:17592138
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processItchIDAMouseMGI:MGI:3038342|PMID:14973438
Biological ProcessGO:0090085regulation of protein deubiquitinationItchIMPMouseMGI:MGI:3774677|PMID:18246070
Biological ProcessGO:0006511ubiquitin-dependent protein catabolic processITCHIDAHumanPMID:15678106
Biological ProcessGO:0006511ubiquitin-dependent protein catabolic processItchIDAMouseMGI:MGI:3614328|PMID:15678106

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory