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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
85014

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:85014

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:85014
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005516calmodulin bindingKCNQ1IDAHumanPMID:18165683
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKCNQ1IDAHumanPMID:12522251
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKCNQ1IDAHumanPMID:10400998
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKCNQ1IDAHumanPMID:11299204
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKCNQ1IDAHumanPMID:8900283
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKCNQ1IDAHumanPMID:9354802
Molecular FunctionGO:0044325ion channel bindingKCNQ1IPIUniProtKB:Q9UJ90HumanPMID:12324418
Molecular FunctionGO:0015271outward rectifier potassium channel activityKcnq1IDARatRGD:1581603|PMID:16133261
Molecular FunctionGO:0005267potassium channel activityKcnq1IDARatRGD:625508|PMID:11804849
Molecular FunctionGO:0005515protein bindingKCNQ1IPIUniProtKB:P15382HumanPMID:19521339
Molecular FunctionGO:0005515protein bindingKcnq1IPIRGD:2956RatRGD:1580497|PMID:15389592
Molecular FunctionGO:0042803protein homodimerization activityKcnq1IDARatRGD:7242917|PMID:20962273
Molecular FunctionGO:0034236protein kinase A catalytic subunit bindingKCNQ1IDAHumanPMID:11799244
Molecular FunctionGO:0034237protein kinase A regulatory subunit bindingKCNQ1IDAHumanPMID:11799244
Molecular FunctionGO:0008157protein phosphatase 1 bindingKCNQ1IDAHumanPMID:11799244
Molecular FunctionGO:0097110scaffold protein bindingKCNQ1IPIUniProtKB:Q99996HumanPMID:11799244
Molecular FunctionGO:0005249voltage-gated potassium channel activityKCNQ1IDAHumanPMID:17289006
Molecular FunctionGO:0005249voltage-gated potassium channel activityKCNQ1IDAHumanPMID:8900283
Molecular FunctionGO:0086089voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarizationKCNQ1IMPHumanPMID:12522251
Molecular FunctionGO:0086008voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarizationKCNQ1IMPHumanPMID:12522251
Molecular FunctionGO:1902282voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationKCNQ1IMPHumanPMID:8528244
Cellular ComponentGO:0016323basolateral plasma membraneKCNQ1IDAHumanPMID:21957902
Cellular ComponentGO:0016323basolateral plasma membraneKcnq1IDARatRGD:2317970|PMID:15843438
Cellular ComponentGO:0030659cytoplasmic vesicle membraneKcnq1IDARatRGD:2317968|PMID:18395087
Cellular ComponentGO:0005769early endosomeKCNQ1IDAHumanPMID:21957902
Cellular ComponentGO:0005887integral component of plasma membraneKcnq1IDARatRGD:625508|PMID:11804849
Cellular ComponentGO:0005770late endosomeKCNQ1IDAHumanPMID:21957902
Cellular ComponentGO:0005764lysosomeKCNQ1IDAHumanPMID:21957902
Cellular ComponentGO:0042383sarcolemmaKcnq1IDARatRGD:1304271|PMID:14670813
Cellular ComponentGO:0008076voltage-gated potassium channel complexKCNQ1IDAHumanPMID:17289006
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnq1IDARatRGD:1580497|PMID:15389592
Cellular ComponentGO:0042589zymogen granule membraneKcnq1IDARatRGD:2317969|PMID:18216164
Biological ProcessGO:0086014atrial cardiac muscle cell action potentialKCNQ1IMPHumanPMID:12522251
Biological ProcessGO:0060048cardiac muscle contractionKCNQ1IMPHumanPMID:8528244
Biological ProcessGO:0072358cardiovascular system developmentKcnq1IMPMGI:MGI:2680653MouseMGI:MGI:3587563|PMID:15004216
Biological ProcessGO:0071320cellular response to cAMPKCNQ1IDAHumanPMID:11299204
Biological ProcessGO:0035690cellular response to drugKCNQ1IDAHumanPMID:9108097
Biological ProcessGO:0016458gene silencingKcnq1IMPMouseMGI:MGI:3054495|PMID:15340049
Biological ProcessGO:0086011membrane repolarization during action potentialKCNQ1IDAHumanPMID:11299204
Biological ProcessGO:0086011membrane repolarization during action potentialKCNQ1IDAHumanPMID:8900283
Biological ProcessGO:0086013membrane repolarization during cardiac muscle cell action potentialKCNQ1IMPHumanPMID:8528244
Biological ProcessGO:0046676negative regulation of insulin secretionKcnq1IDARatRGD:1581603|PMID:16133261
Biological ProcessGO:0060454positive regulation of gastric acid secretionKcnq1IMPRatRGD:1581605|PMID:11313306
Biological ProcessGO:1901381positive regulation of potassium ion transmembrane transportKCNQ1IDAHumanPMID:8900283
Biological ProcessGO:0071435potassium ion exportKCNQ1IDAHumanPMID:10400998
Biological ProcessGO:0071435potassium ion exportKCNQ1IDAHumanPMID:17289006
Biological ProcessGO:0071435potassium ion exportKCNQ1IDAHumanPMID:8900283
Biological ProcessGO:0071805potassium ion transmembrane transportKCNQ1IDAHumanPMID:11299204
Biological ProcessGO:0071805potassium ion transmembrane transportKCNQ1IDAHumanPMID:9354802
Biological ProcessGO:0006813potassium ion transportKcnq1IDARatRGD:1581603|PMID:16133261
Biological ProcessGO:0060372regulation of atrial cardiac muscle cell membrane repolarizationKCNQ1IMPHumanPMID:12522251
Biological ProcessGO:0006349regulation of gene expression by genetic imprintingKcnq1IMPMGI:MGI:2429679MouseMGI:MGI:2389526|PMID:12410230
Biological ProcessGO:0006349regulation of gene expression by genetic imprintingKcnq1IMPMouseMGI:MGI:3054495|PMID:15340049
Biological ProcessGO:0086091regulation of heart rate by cardiac conductionKCNQ1IMPHumanPMID:8528244
Biological ProcessGO:0042391regulation of membrane potentialKcnq1IDARatRGD:625508|PMID:11804849
Biological ProcessGO:0060306regulation of membrane repolarizationKCNQ1IDAHumanPMID:11299204
Biological ProcessGO:0060306regulation of membrane repolarizationKCNQ1IMPHumanPMID:8900283
Biological ProcessGO:0060307regulation of ventricular cardiac muscle cell membrane repolarizationKCNQ1IMPHumanPMID:8528244
Biological ProcessGO:0072347response to anestheticKcnq1IDARatRGD:1581604|PMID:12616988
Biological ProcessGO:0086005ventricular cardiac muscle cell action potentialKCNQ1IMPHumanPMID:8528244

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory