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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7966

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:7966

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:7966
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005515protein bindingTbx1IPIUniProtKB:Q91X20MouseMGI:MGI:4819465|PMID:20463296
Molecular FunctionGO:0005515protein bindingTbx1IPIUniProtKB:P97474MouseMGI:MGI:4848250|PMID:20816801
Molecular FunctionGO:0005515protein bindingTbx1IPIUniProtKB:P28359MouseMGI:MGI:5559282|PMID:22842189
Molecular FunctionGO:0005515protein bindingTbx1IPIUniProtKB:Q61466MouseMGI:MGI:5318804|PMID:22438823
Molecular FunctionGO:0005515protein bindingTbx1IPIUniProtKB:Q924S9MouseMGI:MGI:4879036|PMID:21177346
Molecular FunctionGO:0042803protein homodimerization activityTBX1IDAHumanPMID:11111039
Molecular FunctionGO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA bindingTbx1IDAMouseMGI:MGI:3621085|PMID:16556915
Molecular FunctionGO:0043565sequence-specific DNA bindingTBX1IDAHumanPMID:11111039
Molecular FunctionGO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingTbx1IDAMouseMGI:MGI:3621085|PMID:16556915
Cellular ComponentGO:0005634nucleusTBX1IDAHumanPMID:15703190
Cellular ComponentGO:0005634nucleusTbx1IDAMouseMGI:MGI:3697808|PMID:17164259
Cellular ComponentGO:0005634nucleusTbx1IDAMouseMGI:MGI:3809316|PMID:18816853
Biological ProcessGO:0001525angiogenesisTbx1IMPMGI:MGI:2179136MouseMGI:MGI:2178739|PMID:11971873
Biological ProcessGO:0009952anterior/posterior pattern specificationTbx1IGIMGI:MGI:104686MouseMGI:MGI:3614586|PMID:16399080
Biological ProcessGO:0009952anterior/posterior pattern specificationTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3039048|PMID:15084464
Biological ProcessGO:0035909aorta morphogenesisTbx1IMPMGI:MGI:3664784MouseMGI:MGI:3770747|PMID:17916582
Biological ProcessGO:0035909aorta morphogenesisTbx1IGIMGI:MGI:109344|MGI:MGI:102780|MGI:MGI:99604MouseMGI:MGI:5002778|PMID:21364285
Biological ProcessGO:0048844artery morphogenesisTbx1IGIMGI:MGI:95668MouseMGI:MGI:4358009|PMID:19700621
Biological ProcessGO:0048844artery morphogenesisTbx1IGIMGI:MGI:2444748MouseMGI:MGI:4397600|PMID:19855134
Biological ProcessGO:0048844artery morphogenesisTbx1IMPMGI:MGI:2179190MouseMGI:MGI:2138050|PMID:11242110
Biological ProcessGO:0048844artery morphogenesisTbx1IGIMGI:MGI:99655MouseMGI:MGI:5585355|PMID:24821700
Biological ProcessGO:0001568blood vessel developmentTbx1IMPMGI:MGI:2179136MouseMGI:MGI:1930542|PMID:11242049
Biological ProcessGO:0001568blood vessel developmentTbx1IGIMGI:MGI:104686MouseMGI:MGI:3614586|PMID:16399080
Biological ProcessGO:0001568blood vessel developmentTbx1IMPMouseMGI:MGI:3608154|PMID:16284121
Biological ProcessGO:0048514blood vessel morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:1931408|PMID:11239417
Biological ProcessGO:0001974blood vessel remodelingTbx1IGIMGI:MGI:99604|MGI:MGI:1099809MouseMGI:MGI:3690261|PMID:17000704
Biological ProcessGO:0001708cell fate specificationTbx1IGIMGI:MGI:1351209MouseMGI:MGI:3044254|PMID:15064766
Biological ProcessGO:0001708cell fate specificationTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3039048|PMID:15084464
Biological ProcessGO:0008283cell proliferationTbx1IDAMouseMGI:MGI:3656355|PMID:16914493
Biological ProcessGO:0044344cellular response to fibroblast growth factor stimulusTbx1IMPMouseMGI:MGI:5285152|PMID:20807544
Biological ProcessGO:0090103cochlea morphogenesisTbx1IGIUniProtKB:P62515MouseMGI:MGI:5284768|PMID:18231833
Biological ProcessGO:0090103cochlea morphogenesisTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3765363|PMID:17825816
Biological ProcessGO:0060982coronary artery morphogenesisTbx1IMPMGI:MGI:2179190MouseMGI:MGI:4353596|PMID:18583714
Biological ProcessGO:0007368determination of left/right symmetryTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3621085|PMID:16556915
Biological ProcessGO:0042471ear morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3050165|PMID:15190012
Biological ProcessGO:0048701embryonic cranial skeleton morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3050165|PMID:15190012
Biological ProcessGO:0048703embryonic viscerocranium morphogenesisTBX1IMPHumanPMID:14585638
Biological ProcessGO:0070166enamel mineralizationTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3848106|PMID:19233155
Biological ProcessGO:0030855epithelial cell differentiationTbx1IMPMGI:MGI:2179136MouseMGI:MGI:4848250|PMID:20816801
Biological ProcessGO:0030855epithelial cell differentiationTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3848106|PMID:19233155
Biological ProcessGO:0060325face morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:4822099|PMID:20501333
Biological ProcessGO:0007507heart developmentTBX1IMPHumanPMID:14585638
Biological ProcessGO:0007507heart developmentTbx1IMPMGI:MGI:2179191MouseMGI:MGI:1931408|PMID:11239417
Biological ProcessGO:0007507heart developmentTbx1IMPMGI:MGI:2179136MouseMGI:MGI:2178739|PMID:11971873
Biological ProcessGO:0007507heart developmentTbx1IMPMouseMGI:MGI:4879036|PMID:21177346
Biological ProcessGO:0007507heart developmentTbx1IMPMGI:MGI:2179190MouseMGI:MGI:2138050|PMID:11242110
Biological ProcessGO:0007507heart developmentTbx1IGIMGI:MGI:104686MouseMGI:MGI:3614586|PMID:16399080
Biological ProcessGO:0007507heart developmentTbx1IGIMGI:MGI:109340MouseMGI:MGI:3621085|PMID:16556915
Biological ProcessGO:0007507heart developmentTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3621085|PMID:16556915
Biological ProcessGO:0003007heart morphogenesisTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3656355|PMID:16914493
Biological ProcessGO:0003007heart morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3050165|PMID:15190012
Biological ProcessGO:0003007heart morphogenesisTbx1IMPMGI:MGI:3046792MouseMGI:MGI:3045669|PMID:15175244
Biological ProcessGO:0003007heart morphogenesisTbx1IMPMGI:MGI:3046795MouseMGI:MGI:3640736|PMID:16696966
Biological ProcessGO:0042472inner ear morphogenesisTbx1IMPMGI:MGI:3619149,MGI:MGI:3046196MouseMGI:MGI:3629255|PMID:16600992
Biological ProcessGO:0042472inner ear morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3039048|PMID:15084464
Biological ProcessGO:0042472inner ear morphogenesisTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3530686|PMID:15652707
Biological ProcessGO:0042472inner ear morphogenesisTbx1IMPMGI:MGI:2179136MouseMGI:MGI:2671642|PMID:12913075
Biological ProcessGO:0001945lymph vessel developmentTbx1IMPMGI:MGI:3046793,MGI:MGI:2450311MouseMGI:MGI:4452526|PMID:20439995
Biological ProcessGO:0097152mesenchymal cell apoptotic processTbx1IMPMouseMGI:MGI:5284768|PMID:18231833
Biological ProcessGO:0007498mesoderm developmentTbx1IMPMGI:MGI:2179190MouseMGI:MGI:2138050|PMID:11242110
Biological ProcessGO:0042474middle ear morphogenesisTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3530686|PMID:15652707
Biological ProcessGO:0042474middle ear morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:4822099|PMID:20501333
Biological ProcessGO:0042474middle ear morphogenesisTbx1IMPMGI:MGI:1932522,MGI:MGI:3619149MouseMGI:MGI:3629255|PMID:16600992
Biological ProcessGO:0042693muscle cell fate commitmentTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3809316|PMID:18816853
Biological ProcessGO:0007517muscle organ developmentTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3512717|PMID:15385444
Biological ProcessGO:0048644muscle organ morphogenesisTbx1IGIMGI:MGI:97252MouseMGI:MGI:3849775|PMID:19531352
Biological ProcessGO:0060415muscle tissue morphogenesisTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3849775|PMID:19531352
Biological ProcessGO:0045596negative regulation of cell differentiationTbx1IMPMGI:MGI:2179136MouseMGI:MGI:4943633|PMID:19745164
Biological ProcessGO:2001054negative regulation of mesenchymal cell apoptotic processTbx1IGIUniProtKB:P62515MouseMGI:MGI:5284768|PMID:18231833
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterTbx1IMPMouseMGI:MGI:4453944|PMID:20122914
Biological ProcessGO:0001755neural crest cell migrationTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3530686|PMID:15652707
Biological ProcessGO:0001755neural crest cell migrationTbx1IMPMGI:MGI:2179191MouseMGI:MGI:4822099|PMID:20501333
Biological ProcessGO:0042475odontogenesis of dentin-containing toothTbx1IMPMGI:MGI:2179136MouseMGI:MGI:4848250|PMID:20816801
Biological ProcessGO:0042475odontogenesis of dentin-containing toothTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3848106|PMID:19233155
Biological ProcessGO:0071600otic vesicle morphogenesisTbx1IMPMGI:MGI:3046793MouseMGI:MGI:3703494|PMID:17074316
Biological ProcessGO:0042473outer ear morphogenesisTbx1IMPMGI:MGI:1932522,MGI:MGI:3619149MouseMGI:MGI:3629255|PMID:16600992
Biological ProcessGO:0003151outflow tract morphogenesisTbx1IMPMGI:MGI:3664784MouseMGI:MGI:3770747|PMID:17916582
Biological ProcessGO:0003151outflow tract morphogenesisTbx1IGIMGI:MGI:109344|MGI:MGI:102780|MGI:MGI:99604MouseMGI:MGI:5002778|PMID:21364285
Biological ProcessGO:0003151outflow tract morphogenesisTbx1IMPMGI:MGI:2179190MouseMGI:MGI:4353596|PMID:18583714
Biological ProcessGO:0003148outflow tract septum morphogenesisTbx1IMPMouseMGI:MGI:5285152|PMID:20807544
Biological ProcessGO:0060017parathyroid gland developmentTBX1IMPHumanPMID:14585638
Biological ProcessGO:0007389pattern specification processTbx1IGIMGI:MGI:104686MouseMGI:MGI:3614586|PMID:16399080
Biological ProcessGO:0007389pattern specification processTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3512717|PMID:15385444
Biological ProcessGO:0007389pattern specification processTbx1IMPMGI:MGI:2179190MouseMGI:MGI:3530686|PMID:15652707
Biological ProcessGO:0060037pharyngeal system developmentTBX1IMPHumanPMID:14585638
Biological ProcessGO:0060037pharyngeal system developmentTbx1IGIMGI:MGI:109344|MGI:MGI:102780|MGI:MGI:99604MouseMGI:MGI:5002778|PMID:21364285
Biological ProcessGO:0060037pharyngeal system developmentTbx1IMPMouseMGI:MGI:4879036|PMID:21177346
Biological ProcessGO:0060037pharyngeal system developmentTbx1IMPMGI:MGI:3046793MouseMGI:MGI:3763333|PMID:16141220
Biological ProcessGO:0008284positive regulation of cell proliferationTbx1IMPMGI:MGI:3046793MouseMGI:MGI:3763333|PMID:16141220
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationTbx1IMPMGI:MGI:2179136MouseMGI:MGI:4848250|PMID:20816801
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationTbx1IMPMGI:MGI:3046793MouseMGI:MGI:3703494|PMID:17074316
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationTbx1IMPMouseMGI:MGI:5284768|PMID:18231833
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3765363|PMID:17825816
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3848106|PMID:19233155
Biological ProcessGO:0043410positive regulation of MAPK cascadeTbx1IMPMouseMGI:MGI:5285152|PMID:20807544
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationTbx1IMPMouseMGI:MGI:5284768|PMID:18231833
Biological ProcessGO:0001934positive regulation of protein phosphorylationTbx1IMPMouseMGI:MGI:5285152|PMID:20807544
Biological ProcessGO:0072513positive regulation of secondary heart field cardioblast proliferationTbx1IDAMouseMGI:MGI:4943633|PMID:19745164
Biological ProcessGO:2001037positive regulation of tongue muscle cell differentiationTbx1IMPMouseMGI:MGI:3809313|PMID:18816858
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTbx1IGIMGI:MGI:1344416MouseMGI:MGI:4819465|PMID:20463296
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTbx1IMPMouseMGI:MGI:4453944|PMID:20122914
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTbx1IDAMouseMGI:MGI:4879036|PMID:21177346
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTbx1IGIMGI:MGI:97350MouseMGI:MGI:3621085|PMID:16556915
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTbx1IDAMouseMGI:MGI:3621085|PMID:16556915
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedTbx1IDAMouseMGI:MGI:3045669|PMID:15175244
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedTbx1IDAMouseMGI:MGI:3639368|PMID:16684884
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedTbx1IDAMouseMGI:MGI:3577119|PMID:15703190
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedTbx1IDAMouseMGI:MGI:3604925|PMID:15843409
Biological ProcessGO:2000027regulation of organ morphogenesisTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3848569|PMID:19389367
Biological ProcessGO:2000027regulation of organ morphogenesisTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3697808|PMID:17164259
Biological ProcessGO:2000027regulation of organ morphogenesisTbx1IGIMGI:MGI:99604MouseMGI:MGI:3848569|PMID:19389367
Biological ProcessGO:0006357regulation of transcription from RNA polymerase II promoterTbx1IGIMGI:MGI:109340MouseMGI:MGI:4848250|PMID:20816801
Biological ProcessGO:0048384retinoic acid receptor signaling pathwayTbx1IMPMouseMGI:MGI:3809313|PMID:18816858
Biological ProcessGO:0048752semicircular canal morphogenesisTbx1IGIMGI:MGI:2444748MouseMGI:MGI:4397600|PMID:19855134
Biological ProcessGO:0007605sensory perception of soundTbx1IMPMGI:MGI:1932522,MGI:MGI:3619149MouseMGI:MGI:3629255|PMID:16600992
Biological ProcessGO:0007605sensory perception of soundTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3050165|PMID:15190012
Biological ProcessGO:0035176social behaviorTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3639368|PMID:16684884
Biological ProcessGO:0060023soft palate developmentTBX1IMPHumanPMID:14585638
Biological ProcessGO:0048538thymus developmentTBX1IMPHumanPMID:14585638
Biological ProcessGO:0048538thymus developmentTbx1IMPMGI:MGI:3664784MouseMGI:MGI:3770747|PMID:17916582
Biological ProcessGO:0030878thyroid gland developmentTbx1IGIMGI:MGI:99604MouseMGI:MGI:3848569|PMID:19389367
Biological ProcessGO:0030878thyroid gland developmentTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3050165|PMID:15190012
Biological ProcessGO:0030878thyroid gland developmentTbx1IMPMGI:MGI:2179191MouseMGI:MGI:3697808|PMID:17164259
Biological ProcessGO:0030878thyroid gland developmentTbx1IMPMGI:MGI:2179136MouseMGI:MGI:3848569|PMID:19389367
Biological ProcessGO:0043587tongue morphogenesisTbx1IMPMouseMGI:MGI:3809313|PMID:18816858
Biological ProcessGO:0021644vagus nerve morphogenesisTbx1IMPMGI:MGI:2179136MouseMGI:MGI:4948210|PMID:20939858

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/09/2018
MGI 6.12
The Jackson Laboratory