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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
68449

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:68449

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:68449
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingGata6IDAMouseMGI:MGI:3603876|PMID:16199866
Molecular FunctionGO:0003677DNA bindingGata6IDAMouseMGI:MGI:2158590|PMID:11733512
Molecular FunctionGO:0003677DNA bindingGata6IDAMouseMGI:MGI:3588477|PMID:15987774
Molecular FunctionGO:0003677DNA bindingGata6IDAMouseMGI:MGI:3603876|PMID:16199866
Molecular FunctionGO:0003677DNA bindingGata6IDAMouseMGI:MGI:3628672|PMID:16621466
Molecular FunctionGO:0003677DNA bindingGata6IDAMouseMGI:MGI:3654711|PMID:16912278
Molecular FunctionGO:0003690double-stranded DNA bindingGata6IDARatRGD:2314198|PMID:10851229
Molecular FunctionGO:0001158enhancer sequence-specific DNA bindingGata6IDARatRGD:8554432|PMID:20855530
Molecular FunctionGO:0001158enhancer sequence-specific DNA bindingGata6IDARatPMID:20855530
Molecular FunctionGO:0005515protein bindingGATA6IPIUniProtKB:O88942HumanPMID:11889139
Molecular FunctionGO:0005515protein bindingGATA6IPIUniProtKB:Q9DBX7HumanPMID:16199874
Molecular FunctionGO:0005515protein bindingGATA6IPIUniProtKB:Q9QUS4HumanPMID:16199874
Molecular FunctionGO:0005515protein bindingGATA6IPIUniProtKB:Q9WV93HumanPMID:16199874
Molecular FunctionGO:0005515protein bindingGATA6IPIUniProtKB:Q15648HumanPMID:19497978
Molecular FunctionGO:0005515protein bindingGata6IPIUniProtKB:O88323MouseMGI:MGI:2158098|PMID:11724781
Molecular FunctionGO:0005515protein bindingGata6IPIUniProtKB:P50220MouseMGI:MGI:2158590|PMID:11733512
Molecular FunctionGO:0005515protein bindingGata6IPIUniProtKB:Q8VEE1MouseMGI:MGI:3603876|PMID:16199866
Molecular FunctionGO:0019901protein kinase bindingGATA6IPIUniProtKB:P49841HumanPMID:20864106
Molecular FunctionGO:0000979RNA polymerase II core promoter sequence-specific DNA bindingGata6IDAMouseMGI:MGI:4950308|PMID:21350014
Molecular FunctionGO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityGata6IDAMouseMGI:MGI:81672|PMID:8660897
Molecular FunctionGO:0001103RNA polymerase II repressing transcription factor bindingGata6IPIUniProtKB:Q9UBP5MouseMGI:MGI:3610837|PMID:16293227
Molecular FunctionGO:0043565sequence-specific DNA bindingGata6IDAMouseMGI:MGI:2180986|PMID:11914369
Molecular FunctionGO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activityGATA6IMPHumanPMID:21127043
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityGATA6IDAHumanPMID:19497978
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityGATA6IDAHumanPMID:19666519
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityGata6IDAMouseMGI:MGI:2180986|PMID:11914369
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityGata6IDAMouseMGI:MGI:3628672|PMID:16621466
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityGata6IDAMouseMGI:MGI:3695537|PMID:17164424
Molecular FunctionGO:0008134transcription factor bindingGATA6IPIUniProtKB:P08047HumanPMID:14988427
Molecular FunctionGO:0008134transcription factor bindingGATA6IPIUniProtKB:Q03014HumanPMID:15016828
Molecular FunctionGO:0008134transcription factor bindingGata6IPIUniProtKB:P42586MouseMGI:MGI:3701716|PMID:16887115
Molecular FunctionGO:0008134transcription factor bindingGata6IPIUniProtKB:P46152RatRGD:8553656|PMID:10330176
Molecular FunctionGO:0008134transcription factor bindingGata6IPIUniProtKB:P46152RatPMID:10330176
Molecular FunctionGO:0044212transcription regulatory region DNA bindingGATA6IDAHumanPMID:18177748
Molecular FunctionGO:0044212transcription regulatory region DNA bindingGATA6IDAHumanPMID:19666519
Molecular FunctionGO:0044212transcription regulatory region DNA bindingGATA6IDAHumanPMID:20206639
Molecular FunctionGO:0044212transcription regulatory region DNA bindingGATA6IDAHumanPMID:9566909
Molecular FunctionGO:0044212transcription regulatory region DNA bindingGata6IDARatRGD:8554170|PMID:12606287
Molecular FunctionGO:0044212transcription regulatory region DNA bindingGata6IDARatPMID:12606287
Cellular ComponentGO:0005634nucleusGATA6IDAHumanPMID:17785913
Cellular ComponentGO:0005634nucleusGATA6IDAHumanPMID:19666519
Cellular ComponentGO:0005634nucleusGATA6IDAHumanPMID:20206639
Cellular ComponentGO:0005634nucleusGATA6IDAHumanPMID:21127043
Cellular ComponentGO:0005634nucleusGATA6IDAHumanPMID:21828274
Cellular ComponentGO:0005634nucleusGATA6IDAHumanPMID:9566909
Cellular ComponentGO:0005634nucleusGATA6IDAHumanPMID:9593712
Cellular ComponentGO:0005634nucleusGata6IDAMouseMGI:MGI:2384240|PMID:12130579
Cellular ComponentGO:0005634nucleusGata6IDAMouseMGI:MGI:3603876|PMID:16199866
Cellular ComponentGO:0005634nucleusGata6IDAMouseMGI:MGI:3696911|PMID:16940177
Cellular ComponentGO:0005634nucleusGata6IDAMouseMGI:MGI:4422111|PMID:20123909
Cellular ComponentGO:0005634nucleusGata6IDAMouseMGI:MGI:5002493|PMID:20705924
Cellular ComponentGO:0005634nucleusGata6IDARatRGD:2314198|PMID:10851229
Cellular ComponentGO:0005667transcription factor complexGata6IDAMouseMGI:MGI:3695537|PMID:17164424
Biological ProcessGO:0055007cardiac muscle cell differentiationGata6IGIMGI:MGI:95664MouseMGI:MGI:3790568|PMID:18400219
Biological ProcessGO:0055007cardiac muscle cell differentiationGata6IMPMGI:MGI:3793425MouseMGI:MGI:3790568|PMID:18400219
Biological ProcessGO:0014898cardiac muscle hypertrophy in response to stressGata6IMPMGI:MGI:3654150|MGI:MGI:3054171MouseMGI:MGI:5002493|PMID:20705924
Biological ProcessGO:0048738cardiac muscle tissue developmentGata6IGIMGI:MGI:95664MouseMGI:MGI:5002493|PMID:20705924
Biological ProcessGO:0060947cardiac vascular smooth muscle cell differentiationGATA6IMPHumanPMID:11889139
Biological ProcessGO:0060947cardiac vascular smooth muscle cell differentiationGATA6IMPHumanPMID:12615657
Biological ProcessGO:0071773cellular response to BMP stimulusGata6IDAMouseMGI:MGI:4830625|PMID:20501701
Biological ProcessGO:0071371cellular response to gonadotropin stimulusGata6IDAMouseMGI:MGI:1095695|PMID:9231805
Biological ProcessGO:0071456cellular response to hypoxiaGATA6IDAHumanPMID:21127043
Biological ProcessGO:0060486Clara cell differentiationGata6IGIMGI:MGI:108067MouseMGI:MGI:3695537|PMID:17164424
Biological ProcessGO:0035987endodermal cell differentiationGata6IMPMGI:MGI:2177785MouseMGI:MGI:1315079|PMID:9832509
Biological ProcessGO:0007493endodermal cell fate determinationGata6IDAMouseMGI:MGI:4442295|PMID:20308546
Biological ProcessGO:0030855epithelial cell differentiationGata6IMPMouseMGI:MGI:3701716|PMID:16887115
Biological ProcessGO:0001701in utero embryonic developmentGata6IMPMGI:MGI:2177785MouseMGI:MGI:1315079|PMID:9832509
Biological ProcessGO:0001701in utero embryonic developmentGata6IMPMGI:MGI:3793425MouseMGI:MGI:4422111|PMID:20123909
Biological ProcessGO:0060575intestinal epithelial cell differentiationGATA6IDAHumanPMID:9566909
Biological ProcessGO:0001889liver developmentGata6IMPMGI:MGI:3576383MouseMGI:MGI:3575862|PMID:15767668
Biological ProcessGO:0060430lung saccule developmentGata6IGIMGI:MGI:108067MouseMGI:MGI:3695537|PMID:17164424
Biological ProcessGO:0043066negative regulation of apoptotic processGATA6IMPHumanPMID:21127043
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterGATA6IDAHumanPMID:18177748
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedGATA6IDAHumanPMID:18177748
Biological ProcessGO:0032911negative regulation of transforming growth factor beta1 productionGATA6IMPHumanPMID:21127043
Biological ProcessGO:0032912negative regulation of transforming growth factor beta2 productionGATA6IMPHumanPMID:21127043
Biological ProcessGO:0048645organ formationGata6IMPMouseMGI:MGI:3701716|PMID:16887115
Biological ProcessGO:0003148outflow tract septum morphogenesisGATA6IMPHumanPMID:19666519
Biological ProcessGO:0031016pancreas developmentGata6IMPMouseMGI:MGI:3701716|PMID:16887115
Biological ProcessGO:0003310pancreatic A cell differentiationGata6IMPMouseMGI:MGI:3701716|PMID:16887115
Biological ProcessGO:0006644phospholipid metabolic processGata6IGIMGI:MGI:108067MouseMGI:MGI:3695537|PMID:17164424
Biological ProcessGO:0045766positive regulation of angiogenesisGATA6IDAHumanPMID:21127043
Biological ProcessGO:0043065positive regulation of apoptotic processGata6IMPRatRGD:2314195|PMID:19628789
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayGata6IDARatRGD:8554170|PMID:12606287
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayGata6IDARatPMID:12606287
Biological ProcessGO:0060045positive regulation of cardiac muscle cell proliferationGata6IGIMGI:MGI:102541MouseMGI:MGI:3833786|PMID:19084512
Biological ProcessGO:0071158positive regulation of cell cycle arrestGATA6IDAHumanPMID:9593712
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGATA6IDAHumanPMID:19497978
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IDAMouseMGI:MGI:81672|PMID:8660897
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IDAMouseMGI:MGI:1315079|PMID:9832509
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IMPMGI:MGI:2177785MouseMGI:MGI:1315079|PMID:9832509
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IDAMouseMGI:MGI:2180986|PMID:11914369
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IDAMouseMGI:MGI:3530679|PMID:15539431
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IDAMouseMGI:MGI:3603876|PMID:16199866
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IDAMouseMGI:MGI:3628672|PMID:16621466
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IGIMGI:MGI:108067MouseMGI:MGI:3695537|PMID:17164424
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IGIMGI:MGI:108067MouseMGI:MGI:3709528|PMID:16510470
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IGIMGI:MGI:107516|MGI:MGI:106658MouseMGI:MGI:3709528|PMID:16510470
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IMPMouseMGI:MGI:3828404|PMID:16137232
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IMPMGI:MGI:3623678MouseMGI:MGI:4950308|PMID:21350014
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterGata6IMPRatRGD:2314197|PMID:15591218
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedGata6IDAMouseMGI:MGI:81672|PMID:8660897
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedGata6IDAMouseMGI:MGI:1289810|PMID:9738004
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedGata6IDAMouseMGI:MGI:2158590|PMID:11733512
Biological ProcessGO:0010468regulation of gene expressionGata6IGIMGI:MGI:95664MouseMGI:MGI:3790568|PMID:18400219
Biological ProcessGO:0042493response to drugGATA6IMPHumanPMID:18671946
Biological ProcessGO:0043627response to estrogenGata6IDAMouseMGI:MGI:1095695|PMID:9231805
Biological ProcessGO:0070848response to growth factorGATA6IDAHumanPMID:21127043
Biological ProcessGO:0051145smooth muscle cell differentiationGATA6IMPHumanPMID:17626241
Biological ProcessGO:0006366transcription from RNA polymerase II promoterGATA6IDAHumanPMID:19666519
Biological ProcessGO:0006366transcription from RNA polymerase II promoterGata6IDAMouseMGI:MGI:81672|PMID:8660897
Biological ProcessGO:0035239tube morphogenesisGata6IGIMGI:MGI:95664MouseMGI:MGI:3790568|PMID:18400219
Biological ProcessGO:0003309type B pancreatic cell differentiationGata6IMPMouseMGI:MGI:3701716|PMID:16887115
Biological ProcessGO:0060510Type II pneumocyte differentiationGata6IGIMGI:MGI:108067MouseMGI:MGI:3695537|PMID:17164424

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory