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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
68050

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:68050

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:68050
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003779actin bindingTNNT2IDAHumanPMID:8205619
Molecular FunctionGO:0005515protein bindingTNNT2IPIUniProtKB:Q15014HumanPMID:25416956
Molecular FunctionGO:0030674protein binding, bridgingTnnt2IDARatRGD:1580456|PMID:16443664
Molecular FunctionGO:0005200structural constituent of cytoskeletonTnnt2IDAMouseMGI:MGI:2675179|PMID:12832403
Molecular FunctionGO:0005523tropomyosin bindingTNNT2IDAHumanPMID:10850966
Molecular FunctionGO:0030172troponin C bindingTNNT2IPIUniProtKB:P63316HumanPMID:15542288
Molecular FunctionGO:0030172troponin C bindingTNNT2IPIUniProtKB:P63316HumanPMID:8205619
Molecular FunctionGO:0031013troponin I bindingTNNT2IPIUniProtKB:P19429HumanPMID:15542288
Molecular FunctionGO:0031013troponin I bindingTnnt2IPIRGD:11434RatRGD:1580426|PMID:12501194
Cellular ComponentGO:0097512cardiac myofibrilTNNT2IDAHumanPMID:25771144
Cellular ComponentGO:1990584cardiac Troponin complexTNNT2IDAHumanPMID:25771144
Cellular ComponentGO:0005737cytoplasmTnnt2IDAMouseMGI:MGI:3578095|PMID:15830381
Cellular ComponentGO:0030016myofibrilTnnt2IDAMouseMGI:MGI:3806873|PMID:18781631
Cellular ComponentGO:0030016myofibrilTnnt2IDAMouseMGI:MGI:1342889|PMID:10449439
Cellular ComponentGO:0030016myofibrilTnnt2IDARatRGD:1600178|PMID:11448842
Cellular ComponentGO:0030017sarcomereTnnt2IDAMouseMGI:MGI:5571433|PMID:24364879
Cellular ComponentGO:0030017sarcomereTnnt2IDAMouseMGI:MGI:3611718|PMID:16326803
Cellular ComponentGO:0030017sarcomereTnnt2IDAMouseMGI:MGI:2665243|PMID:12738802
Cellular ComponentGO:0005865striated muscle thin filamentTNNT2IDAHumanPMID:12186860
Cellular ComponentGO:0005861troponin complexTNNT2IDAHumanPMID:12186860
Cellular ComponentGO:0005861troponin complexTnnt2IDAMouseMGI:MGI:2675179|PMID:12832403
Cellular ComponentGO:0005861troponin complexTnnt2IDARatRGD:1580426|PMID:12501194
Biological ProcessGO:0051764actin crosslink formationTnnt2IDARatRGD:1580456|PMID:16443664
Biological ProcessGO:0055009atrial cardiac muscle tissue morphogenesisTnnt2IMPMGI:MGI:3692448|MGI:MGI:3692450|MGI:MGI:3692451MouseMGI:MGI:1342889|PMID:10449439
Biological ProcessGO:0060048cardiac muscle contractionTNNT2IDAHumanPMID:25771144
Biological ProcessGO:0060048cardiac muscle contractionTnnt2IDARatRGD:1600178|PMID:11448842
Biological ProcessGO:0007507heart developmentTnnt2IMPMGI:MGI:3692598|MGI:MGI:3692603MouseMGI:MGI:1267151|PMID:9637714
Biological ProcessGO:0006936muscle contractionTnnt2IDAMouseMGI:MGI:2675179|PMID:12832403
Biological ProcessGO:0006936muscle contractionTnnt2IMPRatRGD:1580425|PMID:16644804
Biological ProcessGO:0030049muscle filament slidingTNNT2IDAHumanPMID:12186860
Biological ProcessGO:0030049muscle filament slidingTNNT2IDAHumanPMID:15923195
Biological ProcessGO:0032780negative regulation of ATPase activityTNNT2IDAHumanPMID:10850966
Biological ProcessGO:0032781positive regulation of ATPase activityTNNT2IDAHumanPMID:10850966
Biological ProcessGO:0032781positive regulation of ATPase activityTNNT2IDAHumanPMID:12186860
Biological ProcessGO:0051291protein heterooligomerizationTnnt2IPIRGD:1309921|RGD:11434RatRGD:1580426|PMID:12501194
Biological ProcessGO:0008016regulation of heart contractionTNNT2IMPHumanPMID:15542288
Biological ProcessGO:0008016regulation of heart contractionTnnt2IMPMGI:MGI:3692450MouseMGI:MGI:1931973|PMID:11158969
Biological ProcessGO:0008016regulation of heart contractionTnnt2IMPMGI:MGI:3693250MouseMGI:MGI:3611718|PMID:16326803
Biological ProcessGO:0006937regulation of muscle contractionTnnt2IDARatRGD:1580456|PMID:16443664
Biological ProcessGO:0032972regulation of muscle filament sliding speedTnnt2IMPRatRGD:8554013|PMID:10747195
Biological ProcessGO:0051592response to calcium ionTNNT2IMPHumanPMID:8205619
Biological ProcessGO:0045214sarcomere organizationTnnt2IMPMGI:MGI:3692448|MGI:MGI:3692450|MGI:MGI:3692451MouseMGI:MGI:1342889|PMID:10449439
Biological ProcessGO:0055010ventricular cardiac muscle tissue morphogenesisTNNT2IMPHumanPMID:16754800
Biological ProcessGO:0055010ventricular cardiac muscle tissue morphogenesisTnnt2IMPMGI:MGI:3693250MouseMGI:MGI:3611718|PMID:16326803

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/16/2019
MGI 6.14
The Jackson Laboratory