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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
669

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:669

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:669
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0008144drug bindingHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Molecular FunctionGO:0008144drug bindingHtr1bIDARatRGD:1626467|PMID:16546225
Molecular FunctionGO:0004993G-protein coupled serotonin receptor activityHTR1BIDAHumanPMID:1315531
Molecular FunctionGO:0004993G-protein coupled serotonin receptor activityHtr1bIDAMouseMGI:MGI:64075
Molecular FunctionGO:0004993G-protein coupled serotonin receptor activityHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Molecular FunctionGO:0004993G-protein coupled serotonin receptor activityHtr1bIDARatRGD:1358659|PMID:15328035
Molecular FunctionGO:0005515protein bindingHTR1BIPIUniProtKB:Q99750HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingHTR1BIPIUniProtKB:Q99750HumanPMID:25910212
Molecular FunctionGO:0051378serotonin bindingHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Molecular FunctionGO:0051378serotonin bindingHtr1bIDARatRGD:2303614|PMID:2947981
Cellular ComponentGO:0005737cytoplasmHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Cellular ComponentGO:0005887integral component of plasma membraneHTR1BIMPHumanPMID:1315531
Cellular ComponentGO:0005886plasma membraneHTR1BIDAHumanGO_REF:0000052
Cellular ComponentGO:0005886plasma membraneHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Cellular ComponentGO:0005886plasma membraneHtr1bIDARatRGD:1358659|PMID:15328035
Biological ProcessGO:0007198adenylate cyclase-inhibiting serotonin receptor signaling pathwayHTR1BIDAHumanPMID:1315531
Biological ProcessGO:0046849bone remodelingHtr1bIGIMGI:MGI:98796|MGI:MGI:1278315MouseMGI:MGI:3836667|PMID:19041748
Biological ProcessGO:0071312cellular response to alkaloidHTR1BIDAHumanPMID:1315531
Biological ProcessGO:0035690cellular response to drugHTR1BIDAHumanPMID:1315531
Biological ProcessGO:0071502cellular response to temperature stimulusHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Biological ProcessGO:0007268chemical synaptic transmissionHtr1bIDARatRGD:1358659|PMID:15328035
Biological ProcessGO:0042756drinking behaviorHtr1bIMPRatRGD:1626464|PMID:16839853
Biological ProcessGO:0007631feeding behaviorHtr1bIMPRatRGD:1626446|PMID:12373419
Biological ProcessGO:0002031G-protein coupled receptor internalizationHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Biological ProcessGO:0030818negative regulation of cAMP biosynthetic processHTR1BIDAHumanPMID:8882600
Biological ProcessGO:0030818negative regulation of cAMP biosynthetic processHtr1bIDAMouseMGI:MGI:64075
Biological ProcessGO:0014063negative regulation of serotonin secretionHtr1bIMPMouseMGI:MGI:1098377|PMID:9349547
Biological ProcessGO:0032229negative regulation of synaptic transmission, GABAergicHtr1bIMPRatRGD:1626455|PMID:17229091
Biological ProcessGO:0051967negative regulation of synaptic transmission, glutamatergicHtr1bIMPRatRGD:1626454|PMID:17392733
Biological ProcessGO:1904707positive regulation of vascular smooth muscle cell proliferationHTR1BIMPHumanPMID:25871906
Biological ProcessGO:0007205protein kinase C-activating G-protein coupled receptor signaling pathwayHtr1bIMPMouseMGI:MGI:4821070|PMID:17325130
Biological ProcessGO:0014059regulation of dopamine secretionHtr1bIMPRatRGD:1626459|PMID:16885935
Biological ProcessGO:0042220response to cocaineHtr1bIDARatRGD:1626452|PMID:17509084
Biological ProcessGO:0042493response to drugHtr1bIDAMouseMGI:MGI:4821070|PMID:17325130
Biological ProcessGO:0045471response to ethanolHtr1bIMPRatRGD:1626469|PMID:16212943
Biological ProcessGO:0009636response to toxic substanceHtr1bIDAMouseMGI:MGI:64075

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory