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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
56412

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:56412

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:56412
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q15717HumanPMID:14517288
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:P26651HumanPMID:15014438
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q00613HumanPMID:16278218
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q16539HumanPMID:17255097
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q9QWH1HumanPMID:19369945
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:O95453HumanPMID:20932473
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q13151HumanPMID:20932473
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:P04792HumanPMID:21575178
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q16539HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q16539HumanPMID:23455922
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:Q16539HumanPMID:23602568
Molecular FunctionGO:0005515protein bindingMAPKAPK2IPIUniProtKB:P04792HumanPMID:8774846
Molecular FunctionGO:0005515protein bindingMapkapk2IPIUniProtKB:P18654MouseMGI:MGI:3761050|PMID:17906627
Molecular FunctionGO:0005515protein bindingMapkapk2IPIUniProtKB:P47811|UniProtKB:Q64028|UniProtKB:Q9QWH1MouseMGI:MGI:3846485|PMID:19369945
Molecular FunctionGO:0004674protein serine/threonine kinase activityMAPKAPK2IDAHumanPMID:14517288
Molecular FunctionGO:0004674protein serine/threonine kinase activityMAPKAPK2IDAHumanPMID:15014438
Molecular FunctionGO:0004674protein serine/threonine kinase activityMAPKAPK2IDAHumanPMID:15850461
Molecular FunctionGO:0004674protein serine/threonine kinase activityMAPKAPK2IDAHumanPMID:20932473
Molecular FunctionGO:0004674protein serine/threonine kinase activityMAPKAPK2IDAHumanPMID:8774846
Molecular FunctionGO:0004674protein serine/threonine kinase activityMAPKAPK2IDAHumanPMID:8846784
Molecular FunctionGO:0004674protein serine/threonine kinase activityMapkapk2IDAMouseMGI:MGI:3761050|PMID:17906627
Molecular FunctionGO:0004674protein serine/threonine kinase activityMapkapk2IDAMouseMGI:MGI:5306322|PMID:12456657
Molecular FunctionGO:0004674protein serine/threonine kinase activityMapkapk2IDAMouseMGI:MGI:5306333|PMID:9628873
Cellular ComponentGO:0005813centrosomeMAPKAPK2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005737cytoplasmMAPKAPK2IDAHumanPMID:20932473
Cellular ComponentGO:0005737cytoplasmMapkapk2IDAMouseMGI:MGI:3521520|PMID:15538386
Cellular ComponentGO:0005737cytoplasmMapkapk2IDAMouseMGI:MGI:5306333|PMID:9628873
Cellular ComponentGO:0005634nucleusMAPKAPK2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusMAPKAPK2IDAHumanPMID:20932473
Cellular ComponentGO:0005634nucleusMapkapk2IDAMouseMGI:MGI:3521520|PMID:15538386
Cellular ComponentGO:0005634nucleusMapkapk2IDAMouseMGI:MGI:5306333|PMID:9628873
Biological ProcessGO:00709353'-UTR-mediated mRNA stabilizationMAPKAPK2IDAHumanPMID:14517288
Biological ProcessGO:00709353'-UTR-mediated mRNA stabilizationMAPKAPK2IDAHumanPMID:15014438
Biological ProcessGO:00709353'-UTR-mediated mRNA stabilizationMAPKAPK2IDAHumanPMID:20932473
Biological ProcessGO:0006974cellular response to DNA damage stimulusMAPKAPK2IMPHumanPMID:20932473
Biological ProcessGO:0035924cellular response to vascular endothelial growth factor stimulusMAPKAPK2IMPHumanPMID:18440775
Biological ProcessGO:0031572G2 DNA damage checkpointMAPKAPK2IMPHumanPMID:20932473
Biological ProcessGO:0006954inflammatory responseMapkapk2IMPMouseMGI:MGI:1352048|PMID:10559880
Biological ProcessGO:0048839inner ear developmentMapkapk2IDAMouseMGI:MGI:5140238|PMID:21795542
Biological ProcessGO:0044351macropinocytosisMapkapk2IMPMouseMGI:MGI:3761050|PMID:17906627
Biological ProcessGO:0048255mRNA stabilizationMapkapk2IMPMGI:MGI:2179724MouseMGI:MGI:2158083|PMID:11741878
Biological ProcessGO:0018105peptidyl-serine phosphorylationMAPKAPK2IDAHumanPMID:15850461
Biological ProcessGO:0006468protein phosphorylationMapkapk2IDAMouseMGI:MGI:5306333|PMID:9628873
Biological ProcessGO:0032675regulation of interleukin-6 productionMapkapk2IMPMouseMGI:MGI:1352048|PMID:10559880
Biological ProcessGO:0032680regulation of tumor necrosis factor productionMAPKAPK2IDAHumanPMID:15014438
Biological ProcessGO:0032680regulation of tumor necrosis factor productionMapkapk2IMPMouseMGI:MGI:1352048|PMID:10559880
Biological ProcessGO:0034097response to cytokineMAPKAPK2IDAHumanPMID:8774846
Biological ProcessGO:0032496response to lipopolysaccharideMapkapk2IMPMouseMGI:MGI:1352048|PMID:10559880
Biological ProcessGO:0032496response to lipopolysaccharideMapkapk2IMPMouseMGI:MGI:3761050|PMID:17906627
Biological ProcessGO:0006950response to stressMAPKAPK2IDAHumanPMID:15014438
Biological ProcessGO:0002224toll-like receptor signaling pathwayMapkapk2IMPMouseMGI:MGI:3761050|PMID:17906627
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayMAPKAPK2IMPHumanPMID:18440775

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory